Storage mites are the main sensitizers among adults in northern Vietnam: Results from a population survey

Lâm, Hoàng Thị; Tường, Nguyễn Văn; Lundbäck, Bo; Rönmark, Eva

doi:10.1111/j.1398-9995.2011.02730.x

Cited by 7 publications

(8 citation statements)

References 5 publications

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“…This is concordant with earlier published data [3,8,15,17]. The higher prevalence of allergic sensitization among young compared to older adults is well-known [27].…”

Section: Discussionsupporting

confidence: 93%

“…The prevalence of allergic sensitization measured by specific IgE in 2009 yielded slightly lower results than by using SPT, especially for cat and dog, but confirmed the sensitization pattern. Several international studies have found house dust mite to be the major airborne allergen [17,23]. In Northern Sweden, however, mites are uncommon due to the cold and dry climate [14,22].…”

Section: Discussionmentioning

confidence: 99%

“…The OLIN questionnaire was used in both surveys, and it has also been used in several international studies [8,16,17]. It has been externally validated against the GA2LEN questionnaire [18].…”

Section: Methodsmentioning

confidence: 99%

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Increase in sensitization to common airborne allergens among adults – two population-based studies 15 years apart

Warm

Lindberg

Lundbäck

et al. 2013

All Asth Clin Immun

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BackgroundStudies on time trends of allergic sensitization among adults are rare. The aim of the study was to compare the prevalence of allergic sensitization to common airborne allergens among adults 15 years apart and to identify risk factors for allergic sensitization.MethodsClinical examinations including skin prick test (SPT) and structured interviews were performed in two random population samples in 1994 and 2009. Furthermore, specific IgE was analyzed in 2009. SPT data were available for 483 subjects in 1994 and for 463 subjects in 2009 in ages 20–60 years. Specific IgE was analyzed in 692 subjects in ages 20–79 years.ResultsSensitization to cat (16% to 26%, p < 0.001), dog (13% to 25%, p < 0.001), birch (13% to 18%, p = 0.031) and timothy (12% to 21%, p < 0.001), based on SPT, increased significantly from 1994 to 2009. Sensitization to any positive SPT increased from 35% to 39%, p = 0.13.The proportion of having ≥3 positive SPT reactions increased from 40% to 56%, p = 0.002. The sensitization pattern yielded similar results based on specific IgE. Risk factors for allergic sensitization were having a family history of allergy (OR 3.1, 95% CI 2.0-4.8 for any positive SPT; OR 2.7, 95% CI 1.8-4.0 for any elevated IgE) and urban living (OR 1.7, 95% CI 1.0-2.7; OR 1.5, 95% CI 1.0-2.4).ConclusionsThe prevalence of allergic sensitization to major airborne allergens as well as multi-sensitization increased significantly between the study years. Young age, a family history of allergy and urban living were significant risk factors for allergic sensitization.

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“…This is concordant with earlier published data [3,8,15,17]. The higher prevalence of allergic sensitization among young compared to older adults is well-known [27].…”

Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Increase in sensitization to common airborne allergens among adults – two population-based studies 15 years apart

Warm

Lindberg

Lundbäck

et al. 2013

All Asth Clin Immun

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“…The high prevalence of dust mite sensitization was consistent with previous studies in Vietnam [ 8 9 17 ]. Consistently with our data, a recent study in northern Vietnam reported a prevalence of sensitization by SPT of 23%, 13%, and 13% to Blo t, Der p, and cockroach, respectively, while sensitization was not associated with asthma [ 8 ].…”

Section: Discussionsupporting

confidence: 91%

Evaluation of skin prick test to screen dust mite sensitization in chronic respiratory diseases in Southern Vietnam

Chu¹,

Godin

Phương³

et al. 2018

Asia Pacific Allergy

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BackgroundIn the view of the epidemic growth of sensitization to indoor allergens in Southern Vietnam, there is a requirement to screen large population.ObjectiveTo evaluate skin prick tests (SPTs) as predictors of positive specific IgE (sIgE) to dust allergens, among patients with chronic respiratory diseases (CRDs).MethodsThe sensitization to Blomia tropicalis (Blo t), Dermatophagoides pteronissinus (Der p), and Blattella germanica allergens (Bla g) were evaluated among 610 CRD, both SPT (≥4 mm) and sIgE by immuno-CAP (≥0.7 kUA/L).ResultsBased on sIgE, 45%, 32%, and 33% of patients with CRD were sensitized to Blo t, Der p, and Bla g, respectively, compared to 19%, 18%, and 13% by SPT. The association between SPT and sIgE was statistically significant, though the Kappa factor was fair (i.e., 0.39 to 0.23). While the specificity of SPT to detect sensitization (compared to sIgE) was >90% among the whole population, the sensitivity was only 34%, 41%, and 24% for Bo t, Der p, and Bla g, suggesting that SPT was not enough sensitive to screen the indoor allergen sensitization. Though, among the <10 pack-year (PY) smokers, the sensitivity was 43% for Blo t, 52% for Der p, and 61% for Blo t and/or Der p, compared to 27%, 30%, and 35% among the ≥10 PY smokers. The sensitivity/specificity was not associated with the diagnosis of asthma compared to chronic obstructive pulmonary disease.ConclusionIn the present circumstance, SPT to dust mites allergens can be used to detect a sensitization among CRD population in Southern Vietnam.

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“…This pattern was seen also in the first population based study of sensitization in adults in Northern Vietnam, and we recently presented the crude prevalence measures in a short report [11]. To date, the impact of sensitization on allergic symptoms and conditions in the general adult population in this area has not been studied.…”

Section: Introductionmentioning

confidence: 69%

Sensitization to airborne allergens among adults and its impact on allergic symptoms: a population survey in northern Vietnam

Lâm

Ekerljung

Bjerg

et al. 2014

Clinical & Translational All

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BackgroundThe knowledge about allergic sensitization and its relationship with clinical symptoms and diseases among adults in South-East Asia is poor. The aim of this study was to investigate the prevalence and pattern of allergic sensitization and the association with asthma and allergic rhinitis in adults in urban and rural Vietnam.MethodsAmong 5,782 responders to a questionnaire survey in northern Vietnam, a random sample was invited to a clinical follow-up and 684 (46%) participated. The methods included a structured interview using a modified GA2LEN study questionnaire on symptoms and possible determinants for diseases. Skin prick test (SPT) with ten common airborne indoor and outdoor allergens, lung function test, and methacholine test was performed among subjects ≤60 years of age.ResultsIn total, one third of subjects had a positive SPT reaction to at least one allergen, 36.9% of men and 31.0% of women (n.s.). The most common sensitizer was the storage mite B. tropicalis (men 27.7%; women 18.7%) followed by house dust mite D. pteronyssinus (men 16.5%; women 10.6%), and D. farinae (men 15.3%; women 6.3%), and cockroach (men 16.5%; women 10.2%). Sensitization to all major allergens were significantly more common among men and among subjects ≤45 years compared with women and subjects >45 years, respectively. The prevalence of sensitization to animals, pollen and molds were low. The majority of cockroach-sensitized subjects were also sensitized to mites. Sensitization to any allergen and all major allergens were significantly associated with rhinitis, but not with asthma. However, bronchial hyper-reactivity was significantly associated with increasing number of positive SPTs (p = 0.047).ConclusionsAmong adults in northern Vietnam sensitization to mite and cockroach most common in both rural and urban areas. The dominant sensitizer was the storage mite B. tropicalis, which should be included in future studies and also in clinical practice, owing to its association with clinical symptoms. As in the Western world allergic sensitization was associated with rhinitis and bronchial hyper-reactivity. The lack of association with asthma in South-East Asia needs to be studied further.

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Storage mites are the main sensitizers among adults in northern Vietnam: Results from a population survey

Abstract: [Correction added after online publication 18 October 2011. Author names corrected]

Cited by 7 publications

References 5 publications

Increase in sensitization to common airborne allergens among adults – two population-based studies 15 years apart

Increase in sensitization to common airborne allergens among adults – two population-based studies 15 years apart

Evaluation of skin prick test to screen dust mite sensitization in chronic respiratory diseases in Southern Vietnam

Sensitization to airborne allergens among adults and its impact on allergic symptoms: a population survey in northern Vietnam

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