Strain Differences in the Mammary Tumour‐Inducing Virus as Detected by the Characters and Behaviour of Neoplasms

Squartini, F; Severi, L

doi:10.1002/9780470719275.ch5

Cited by 13 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, other types of hyperplastic lesions were noted. Plaques are found in several mouse strains, such as RIII, GR and DD (Foulds 1956;Squartini and Severi 1962;Muhlbock 1965). These lesions are pregnancy dependent lesions that will progress to pregnancy-independent growths upon recurrence or serial transplantation.…”

Section: Pathobiology Of Mammary Tumorigenesismentioning

confidence: 99%

Of Mice and Women: A Short History of Mouse Mammary Cancer Research with an Emphasis on the Paradigms Inspired by the Transplantation Method

Medina¹

2010

Cold Spring Harbor Perspectives in Biology

View full text Add to dashboard Cite

The ability to transplant mammary epithelial cells of any age or developmental stage to the normal anatomical site of an inbred recipient mouse strain has revolutionized the studies of mammary development and tumor biology over the past 50 years. This simple method has made the mammary gland of the rodent one of the most accessible and studied organs and facilitated our understanding of the fundamental cellular and molecular properties of normal and neoplastic development. This short review outlines the early concepts that led to the development of the transplantation technology and the impact of this method on our understanding for a variety of processes important both for the normal development and differentiation of the gland as well as the phenomena of neoplastic progression.

show abstract

Section: Pathobiology Of Mammary Tumorigenesismentioning

confidence: 99%