Strain Echocardiography Improves Risk Prediction of Ventricular Arrhythmias After Myocardial Infarction

Haugaa, Kristina H.; Grenne, Bjørnar; Eek, Christian; Ersbøll, Mads; Valeur, Nana; Svendsen, Jesper Hastrup; Florian, Anca; Sjøli, Benthe; Brunvand, Harald; Køber, Lars; Voigt, Jens‐Uwe; Desmet, Walter; Smiseth, Otto A.; Edvardsen, Thor

doi:10.1016/j.jcmg.2013.03.005

Cited by 248 publications

(181 citation statements)

References 27 publications

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“…8 In addition, a heterogeneous myocardial contraction pattern determined by a dyssynchronic ventricular contraction (known as MD or dyssynchrony) has also been demonstrated useful to predict ventricular arrhythmias. 6,7 In contrast to previous studies, [24][25][26] we did not find MD to be a strong predictor of ventricular tachyarrhythmias (Table 2). This might be because of the fact that we only obtained MD from 12 segments (apical 4-and 2-chamber views) instead of 18 segments or because 2DSE was performed on Digital Imaging and Communications in Medicine images leading to lower frame rates than used in previous studies.…”

Section: Myocardial Deformation and Prognosiscontrasting

confidence: 99%

“…[6][7][8]11 However, both GLS and mechanical dispersion (MD) are based on averaging regional differences in deformation timing and amplitude, and important abnormalities in regional function may be missed by dilution in this process. Furthermore, the local radius of curvature of the ventricle increases from the apex to the base of the heart and also from the lateral to the septal wall.…”

Section: Biering-sørensen Et Almentioning

confidence: 99%

See 1 more Smart Citation

Regional Longitudinal Deformation Improves Prediction of Ventricular Tachyarrhythmias in Patients With Heart Failure With Reduced Ejection Fraction

Knappe

Pouleur

Claggett

et al. 2017

Circ: Cardiovascular Imaging

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Background— Left ventricular dysfunction is a known predictor of ventricular arrhythmias. We hypothesized that measures of regional longitudinal deformation by speckle-tracking echocardiography predict ventricular tachyarrhythmias and provide incremental prognostic information over clinical and conventional echocardiographic characteristics. Methods and Results— We studied 1064 patients enrolled in the MADIT-CRT trial (Multicenter Automatic Defibrillator Implantation Trial-Cardiac Resynchronization Therapy) with speckle-tracking data available. Peak longitudinal strain was obtained for the septal, lateral, anterior, and inferior myocardial walls at baseline. The end point was the first event of ventricular tachycardia (VT) or fibrillation (VF). During the median follow-up of 2.9 years, 254 (24%) patients developed VT/VF. Patients with VT/VF had significantly lower left ventricular ejection fraction (28.3% versus 29.5%; P <0.001) and longitudinal strain in all myocardial walls compared with patients without VT/VF (anterior-strain, −7.7% versus −8.8%; P <0.001; lateral-strain, −7.3% versus −7.9%; P =0.022; inferior-strain, −8.3% versus −9.9%; P <0.001; septal-strain, −9.1% versus −10.0%; P <0.001). After multivariate adjustment, only anterior and inferior longitudinal strain remained independent predictors of VT/VF (anterior: hazard ratio, 1.08 [1.03–1.13]; P =0.001; inferior: hazard ratio, 1.08 [1.04–1.12]; P <0.001; per 1% absolute decrease for both). When including B-type natriuretic peptide in the model, only a decreasing myocardial function in the inferior myocardial wall predicted VT/VF (hazard ratio, 1.05 [1.00–1.11]; P =0.039). Only strain obtained from the inferior myocardial wall provided incremental prognostic information for VT/VF over clinical and echocardiographic parameters (C statistic 0.71 versus 0.69; P =0.005). Conclusions— Assessment of regional longitudinal myocardial deformation in the inferior region provided incremental prognostic information over clinical and echocardiographic risk factors in predicting ventricular tachyarrhythmias. Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00180271.

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Section: Myocardial Deformation and Prognosiscontrasting

confidence: 99%

Section: Biering-sørensen Et Almentioning

confidence: 99%

Regional Longitudinal Deformation Improves Prediction of Ventricular Tachyarrhythmias in Patients With Heart Failure With Reduced Ejection Fraction

Knappe

Pouleur

Claggett

et al. 2017

Circ: Cardiovascular Imaging

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“…Гетерогенность времени до пикового стрейна среди сегментов ЛЖ ассоциируется с возникновением желудочковых нарушений рит-ма, а механическая дисперсия  75 мс позволяет предсказать опасные желудочковые нарушения ритма и провести отбор пациентов для импланта-ции кардиовертера-дефибриллятора при ФВ ЛЖ больше 35 % (рис. 8) [30].…”

Section: спекл-трекинг эхокардиография при ишемической болезни сердцаunclassified

Роль Спекл-Трекінг Ехокардіографії В Діагностиці Та Лікуванні Серцево-Судинних Захворювань

Nesukai

Danylenko

2021

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“…A promising alternative strategy to understanding the risk of arrhythmia and sudden cardiac death has been the evaluation of myocardial fibrosis. It appears that heterogeneous scarring is an important driver of arrhythmia, and it appears that temporal dispersion of myocardial contraction-which can be measured by strain-parallels the magnitude of this problem (42,43).…”

Section: Implantable Cardioverter Defibrillatorsmentioning

confidence: 99%

The Role of Echocardiography in Heart Failure

Marwick¹

2015

J Nucl Med

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Data from echocardiography provide a cornerstone in the management of heart failure. All imaging techniques can provide an ejection fraction, but the versatility of echocardiography makes it unique in the provision of volumes, diastolic function, right ventricular function, hemodynamics, and valvular regurgitation. The early detection of heart failure has been facilitated by the assessment of global longitudinal strain, which is also useful in later heart failure for the assessment of left ventricular synchrony. The use of echocardiography has been associated with favorable outcomes, probably on the basis of facilitation of appropriate therapy. This review examines the evidence provided by echocardiography and its application in specific settings. Although the guidelines emphasize that no single test satisfies all imaging requirements in heart failure, and other modalities can provide additional information about specific questions (especially tissue characterization), echocardiography is indispensable in the management of heart failure.

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Strain Echocardiography Improves Risk Prediction of Ventricular Arrhythmias After Myocardial Infarction

Cited by 248 publications

References 27 publications

Regional Longitudinal Deformation Improves Prediction of Ventricular Tachyarrhythmias in Patients With Heart Failure With Reduced Ejection Fraction

Regional Longitudinal Deformation Improves Prediction of Ventricular Tachyarrhythmias in Patients With Heart Failure With Reduced Ejection Fraction

Роль Спекл-Трекінг Ехокардіографії В Діагностиці Та Лікуванні Серцево-Судинних Захворювань

The Role of Echocardiography in Heart Failure

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