Biomimetics 2013
DOI: 10.1002/9781118810408.ch6
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Strategy for a Biomimetic Paradigm in Dental and Craniofacial Tissue Engineering

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Cited by 5 publications
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“…4,5 This is mostly due to the large size of defect that results from tumor excision with adequate safety margins and due to the defective vascularity in the region after possible irradiation. 6,7 As regenerative medicine depends primarily on harnessing the body's regenerative capacity to replace the lost tissues, providing adequate vascularization of the construct (scaffold) that is used to bridge the defect is a determining issue. 8 The socalled "axially vascularized tissue engineering constructs" (AV-TECs) aim at providing adequate blood supply especially to the central regions of large defects independent of the vascularity of the local tissues, and thus represent a promising option for reconstruction of larger defects in poorly vascularized areas as it is the case after irradiation.…”
mentioning
confidence: 99%
“…4,5 This is mostly due to the large size of defect that results from tumor excision with adequate safety margins and due to the defective vascularity in the region after possible irradiation. 6,7 As regenerative medicine depends primarily on harnessing the body's regenerative capacity to replace the lost tissues, providing adequate vascularization of the construct (scaffold) that is used to bridge the defect is a determining issue. 8 The socalled "axially vascularized tissue engineering constructs" (AV-TECs) aim at providing adequate blood supply especially to the central regions of large defects independent of the vascularity of the local tissues, and thus represent a promising option for reconstruction of larger defects in poorly vascularized areas as it is the case after irradiation.…”
mentioning
confidence: 99%