2019
DOI: 10.34051/p/2019.5
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Structural analysis of allosteric regulation of the regulatory GAF domains of cone photoreceptor phosphodiesterase-6 (PDE6) by cGMP and the inhibitory γ-subunit

Abstract: Structural analysis of the regulatory GAF domains of cGMP phosphodiesterase elucidates the allosteric communication pathway" (2019). Faculty Publications. 705. AbstractRegulation of photoreceptor phosphodiesterase (PDE6) activity is responsible for the speed, sensitivity, and recovery of the photoresponse during visual signaling in vertebrate photoreceptor cells. It is hypothesized that the physiological differences in the light responsiveness of rods and cones may result in part from differences in the struct… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 36 publications
(50 reference statements)
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?