Structural and functional diversity of lectins associated with immunity in the marine shrimp Litopenaeus vannamei

Viana, Jhonatas Teixeira; Rocha, Rafael dos Santos; Maggioni, Rodrigo

doi:10.1016/j.fsi.2022.08.051

Cited by 18 publications

(5 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our data show that when compared with unvaccinated shrimp, ALF gene expression was increased 15.4-fold 14 days after oral vaccination with the VP28expressing C. vulgaris (Figure 5a). CTL, which promotes phagocytosis and aggregation, exhibits antiviral activity [48]. Like ALF, treating WSSV-infected shrimp with CTL significantly reduced their mortality [49].…”

Section: Discussionmentioning

confidence: 99%

Efficacy of White Spot Syndrome Virus Protein VP28-Expressing Chlorella vulgaris as an Oral Vaccine for Shrimp

Kim,

Kim

et al. 2023

Viruses

View full text Add to dashboard Cite

The white spot syndrome virus (WSSV) is the causative agent of white spot disease, which kills shrimp within a few days of infection. Although WSSV has a mortality rate of almost 100% and poses a serious threat to the shrimp farming industry, strategies for its prevention and treatment are extremely limited. In this study, we examined the efficacy of VP28, a recombinant WSSV protein expressed in Chlorella vulgaris (C. vulgaris), as an oral shrimp vaccine. When compared with the control group, in which WSSV had a cumulative mortality of 100%, shrimp treated with 5% VP28-expressing C. vulgaris in their feed only had a 20% cumulative mortality rate 12 days after the WSSV challenge. When compared with the nonvaccinated group, the transcription of anti-lipopolysaccharide factor, C-type lectin, and prophenoloxidase genes, which are involved in shrimp defense against WSSV infection, was upregulated 29.6 fold, 15.4 fold, and 11.5 fold, respectively. These findings highlight C. vulgaris as a potential host for industrial shrimp vaccine production.

show abstract

Section: Discussionmentioning

confidence: 99%

Efficacy of White Spot Syndrome Virus Protein VP28-Expressing Chlorella vulgaris as an Oral Vaccine for Shrimp

Kim,

Kim

et al. 2023

Viruses

View full text Add to dashboard Cite

show abstract

“…These reactions involve various receptor molecules, such as lectins and toll-like receptors, which are responsible for detecting the presence of causative agents [ 7 , 8 , 9 ]. Among these receptors, lectins, a group of proteins that bind to carbohydrates, play a vital role in innate immunity by performing multiple functions in host defense [ 10 , 11 , 12 , 13 ]. By recognizing and binding to the carbohydrates on pathogenic bacteria, lectins actively become involved in immune responses, including agglutination, complement activation, inflammation regulation, and clearance of causative agents [ 6 , 14 , 15 , 16 , 17 ].…”

Section: Introductionmentioning

confidence: 99%

Collectin-K1 Plays a Role in the Clearance of Streptococcus agalactiae in Nile Tilapia (Oreochromis niloticus)

Mo,

Li,

Qiu

et al. 2024

IJMS

View full text Add to dashboard Cite

Collectin-K1 (CL-K1) is a multifunctional C-type lectin that has been identified as playing a crucial role in innate immunity. It can bind to carbohydrates on pathogens, leading to direct neutralization, agglutination, and/or opsonization, thereby inhibiting pathogenic infection. In this study, we investigated a homolog of CL-K1 (OnCL-K1) in Nile tilapia (Oreochromis niloticus) and its role in promoting the clearance of the pathogen Streptococcus agalactiae (S. agalactiae) and enhancing the antibacterial ability of the fish. Our analysis of bacterial load displayed that OnCL-K1 substantially reduced the amount of S. agalactiae in tissues of the liver, spleen, anterior kidney, and brain in Nile tilapia. Furthermore, examination of tissue sections revealed that OnCL-K1 effectively alleviated tissue damage and inflammatory response in the liver, anterior kidney, spleen, and brain tissue of tilapia following S. agalactiae infection. Additionally, OnCL-K1 was found to decrease the expression of the pro-inflammatory factor IL-6 and migration inhibitor MIF, while increasing the expression of anti-inflammatory factor IL-10 and chemokine IL-8 in the spleen, anterior kidney, and brain tissues of tilapia. Moreover, statistical analysis of survival rates demonstrated that OnCL-K1 significantly improved the survival rate of tilapia after infection, with a survival rate of 90%. Collectively, our findings suggest that OnCL-K1 plays a vital role in the innate immune defense of resisting bacterial infection in Nile tilapia. It promotes the removal of bacterial pathogens from the host, inhibits pathogen proliferation in vivo, reduces damage to host tissues caused by pathogens, and improves the survival rate of the host.

show abstract

“…Whiteleg shrimp (Penaeus vannamei) is the predominant species in contemporary shrimp aquaculture, accounting for more than half of all produced and consumed crustaceans globally. 1 Live fish and crustaceans are especially appreciated in Asia and other niche markets, 2 making transportation of fresh aquatic products an activity that generates a lot of attention. In accordance with customary commercial transportation practices in China, captured shrimp are typically placed in oxygenated water and transported to the final point of sale.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Impacts of long‐time transportation on whiteleg shrimp (Penaeus vannamei) muscle quality and underlying biochemical mechanisms

et al. 2023

View full text Add to dashboard Cite

BACKGROUNDShrimp is widely consumed around the world. Since muscle is the primary edible component of shrimp, muscle quality (particularly texture) has a direct impact on the economic value of shrimp products. However, reports on the shrimp muscle quality influenced by transportation are rather limited, and the underlying mechanism remains unknown.RESULTSDuring the simulated transportation, the water pH and total ammonia‐nitrogen content and un‐ionized ammonia contents were elevated. Furthermore, reductions in shrimp muscle water‐holding capacity, hardness, and shear value with intensive myofibrillar protein degradation were detected. Simulated transportation decreased the pH and glycogen content of shrimp muscle while increasing lactic dehydrogenase activity and lactate content, resulting in an elevated level of free calcium ions and increased μ‐calpain and general proteolytic activities. Water exchange could improve the water quality and reduce the mortality of shrimp during transportation, as well as decrease muscle textural softening by alleviating these stress responses.CONCLUSIONSMaintaining water quality and, in particular, reducing ammonia are critical to improving shrimp survival and muscle quality during live transportation. This study is of great significance for the better maintenance of the textural properties of shrimp meat. © 2023 Society of Chemical Industry.

show abstract

Structural and functional diversity of lectins associated with immunity in the marine shrimp Litopenaeus vannamei

Cited by 18 publications

References 76 publications

Efficacy of White Spot Syndrome Virus Protein VP28-Expressing Chlorella vulgaris as an Oral Vaccine for Shrimp

Efficacy of White Spot Syndrome Virus Protein VP28-Expressing Chlorella vulgaris as an Oral Vaccine for Shrimp

Collectin-K1 Plays a Role in the Clearance of Streptococcus agalactiae in Nile Tilapia (Oreochromis niloticus)

Impacts of long‐time transportation on whiteleg shrimp (Penaeus vannamei) muscle quality and underlying biochemical mechanisms

Contact Info

Product

Resources

About