Structural and Functional Indicators of Echocardiography in Healthy Representatives of Indigenous and Non-Organized Urbanized Population of Gornaya Shoria

Abstract

Aim: To study the structural and functional parameters of echocardiography in healthy representatives of the urban Shor population, including men and women.Material and Methods. The study included 96 indigenous and 66 non-indigenous urbanized residents of Gornaya Shoria, matched by age and divided according to ethnic and gender characteristics into 4 groups: indigenous men (n=40), indigenous women (n=56), non-indigenous men (n=32), and non-indigenous women (n=34). All individuals underwent echocardiographic study. Body surface area-indexed left and right heart structural parameters, pulse wave Doppler data, data on propagation atrioventricular flow rates, and spectral Doppler tissue data were studied.Results. According to the results of anthropometry, men and women of Shor nationality had a lower body mass and body surface area compared with the corresponding values in men and women of non-indigenous nationality (p<0.0001 in all cases). However, the indices of the thickness of the interventricular septum, the posterior wall of the left ventricle, left ventricular mass and stroke volume, the diameter of the aorta, and the anterior-posterior dimension of the right ventricle were significantly higher in the group of indigenous women compared to non-indigenous ethnic groups. (p<0.01 in all cases). The values of the left ventricular end-diastolic volume, left atrial volume, pulmonary artery diameter were significantly higher in both men and women of indigenous nationality relative to the corresponding female and male comparison groups (p<0.01 in both cases). The tricuspid flow propagation velocity in male Shors was significantly higher than that in non-indigenous men (p<0.01). The Shor nationality was associated with a decrease in body surface area and increases in aortic diameter indices, pulmonary artery, left ventricular posterior wall, left ventricular myocardial mass index, pulmonary artery index, right atrial area index, and tricuspid flow propagation velocity; only a decrease in body surface area was associated with the female sex.Conclusion. In healthy representatives of the indigenous population of Gornaya Shoria, ethnic differences in the structural and functional parameters of echocardiography prevailed over gender-related differences.

Ethnic differences in right ventricular structure and function in urbanized hypertensive patients in the Gornaya Shoriya region

“…Our previous study assessed the state of the right heart in healthy individuals of the Shor nationality 21 . In that study, an increase in the dimensions of the pulmonary artery and right ventricle was found in Shor men and women compared to Caucasians.…”

“…Changes in the structure and function of the heart may not only be caused by genetic characteristics of a particular ethnic group, but also by peculiarities of the lifestyle (for example, traditional lifestyle of ethnic groups), living conditions (countryside / city, highlands / plain), as well as influence of pathological conditions. Previous studies have studied the features of echocardiography in representatives of two ethnic groups of the Gornaya Shoria region—the indigenous population (Shors) and the non-indigenous population (Caucasians) living both in rural areas 3 , 4 and in the city 21 , (Sumin et al, in press). While the ethnic differences in left ventricular echocardiographic parameters were studied both for healthy urban residents of these groups 21 and for patients with arterial hypertension (Sumin AN, in press), the indicators of the right ventricle were only compared in healthy individuals 21 .…”

“…Previous studies have studied the features of echocardiography in representatives of two ethnic groups of the Gornaya Shoria region—the indigenous population (Shors) and the non-indigenous population (Caucasians) living both in rural areas 3 , 4 and in the city 21 , (Sumin et al, in press). While the ethnic differences in left ventricular echocardiographic parameters were studied both for healthy urban residents of these groups 21 and for patients with arterial hypertension (Sumin AN, in press), the indicators of the right ventricle were only compared in healthy individuals 21 . Accordingly, the aim of this study was to compare right ventricular echocardiography parameters in urbanized hypertensive patients of the Shor and non-indigenous ethnic groups.…”

Ethnic differences in right ventricular structure and function in urbanized hypertensive patients in the Gornaya Shoriya region

“…Our previous study assessed the state of the right heart in healthy individuals of the Shor nationality [21].…”

“…Changes in the structure and function of the heart may not only be caused by genetic characteristics of a particular ethnic group, but also by peculiarities of the lifestyle (for example, traditional lifestyle of ethnic groups), living conditions (countryside / city, highlands / plain), as well as in uence of pathological conditions. Previous studies have studied the features of echocardiography in representatives of two ethnic groups of the Gornaya Shoria region -the indigenous population (Shors) and the non-indigenous population (Caucasians) living both in rural areas [3,4] and in the city [21], (Sumin et al, in press). While the ethnic differences in left ventricular echocardiographic parameters were studied both for healthy urban residents of these groups [21] and for patients with arterial hypertension (Sumin AN, in press), the indicators of the right ventricle were only compared in healthy individuals [21].…”