Structural and microstructural characterization of human kidney stones from eastern India using IR spectroscopy, scanning electron microscopy, thermal study and X-ray Rietveld analysis

Ghosh, Soumen; Basu, Sharmila; Chakraborty, Subrata; Mukherjee, Alok K.

doi:10.1107/s0021889809016446

Cited by 28 publications

(21 citation statements)

References 26 publications

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“…Brushite has the biggest crystallite size and the smallest value of relative standard deviation that could be understood as indication of a unified growth mechanism by which this mineral appears in either single or multiphase phosphate stones. Finally, the values of average crystallite sizes found by us for oxalates and apatite kidney stones are in good agreement with the previously reported data of Ghosh et al (2009).…”

Section: Resultssupporting

confidence: 90%

X-ray diffraction and SEM study of kidney stones in Israel: quantitative analysis, crystallite size determination, and statistical characterization

Uvarov

Popov

Shapur

et al. 2011

Environ Geochem Health

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Urinary calculi have been recognized as one of the most painful medical disorders. Tenable knowledge of the phase composition of the stones is very important to elucidate an underlying etiology of the stone disease. We report here the results of quantitative X-ray diffraction phase analysis performed on 278 kidney stones from the 275 patients treated at the Department of Urology of Hadassah Hebrew University Hospital (Jerusalem, Israel). Quantification of biominerals in multicomponent samples was performed using the normalized reference intensity ratio method. According to the observed phase compositions, all the tested stones were classified into five chemical groups: oxalates (43.2%), phosphates (7.7%), urates (10.3%), cystines (2.9%), and stones composed of a mixture of different minerals (35.9%). A detailed analysis of each allocated chemical group is presented along with the crystallite size calculations for all the observed crystalline phases. The obtained results have been compared with the published data originated from different geographical regions. Morphology and spatial distribution of the phases identified in the kidney stones were studied with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). This type of detailed study of phase composition and structural characteristics of the kidney stones was performed in Israel for the first time.

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Section: Resultssupporting

confidence: 90%

X-ray diffraction and SEM study of kidney stones in Israel: quantitative analysis, crystallite size determination, and statistical characterization

Uvarov

Popov

Shapur

et al. 2011

Environ Geochem Health

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“…XRD has advantages of reliability in qualitative analysis, and accuracy in quantitative analysis; being the choice test for the determination of crystal types in HKS [69,70]. In Figure 6, it is possible to observe diffraction peaks that are attributable to both COD as COM crystals.…”

Section: Resultsmentioning

confidence: 99%

Effect of Diazotated Sulphonated Polystyrene Films on the Calcium Oxalate Crystallization

et al. 2017

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Pathological crystallization of calcium oxalate (CaOx) inside the urinary tract is called calculi or kidney stone (Urolithiasis). CaOx exhibits three crystalline types in nature: CaOx monohydrate COM, dihydrate COD and trihydrate COT. COD and COM are often found in urinary calculi, particularly COM. Langmuir monolayers, membrane vesicles, phospholipids' micelles, among others, have been adopted as simplified biomimetic template-models to study in vitro the urolithiasis through CaOx. The nucleation and crystal growth of COM on self-assembled lipid monolayers have revealed that the negatively charged phosphatidylserine interface is a strong promoter of COM. Herein, we describe the synthesis and physicochemical characterization of diazotated sulphonated polystyrene films (DSPFs), prepared from various aminocompounds varying their polarity degree i.e., polar, non-polar and acidic DSPF derivatives. We also used these DSPFs as polymeric templates in crystallization experiments of CaOx in vitro. Images obtained by optical microscopy and scanning electron microscopy confirmed the precipitation of COM crystals on the DSPF surface. The employment of functionalized polymeric films as templates for CaOx crystallization represents a viable approach for understanding inorganic mineralization.

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“…ESEM has been used as an investigation tool in numerous in vitro as well as in vivo investigations [76]. The former helps to describe the morphology of crystals as a function of supersaturation [77], phase conversion processes [78,79], or the effect of uric acid seeds on calcium oxalate formation [80].…”

Section: Discussionmentioning

confidence: 99%

Type 2 diabetes and uric acid stones: A powder neutron diffraction investigation

Daudon

Letavernier

Weil

et al. 2015

Comptes Rendus. Chimie

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a b s t r a c tRecent epidemiologic investigations have identified an association between type 2 diabetes and uric acid kidney stones. This association was more apparent in women than in men. In this paper, we show through powder neutron diffraction that particle sizes of uric acid kidney stones were significantly different between male and female patients (84.7 ± 5.3 vs. 140.2 ± 6.7 nm, p ¼ 0.000003). Interestingly, when type 2 diabetes appeared, this structural difference between male and female vanished (76.1 ± 3.9 vs. 78.8 ± 4.2 nm, not significant). Thus, the complete set of structural data is in line with observations regarding epidemiological data. Some explanations based on supersaturation are discussed.

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Structural and microstructural characterization of human kidney stones from eastern India using IR spectroscopy, scanning electron microscopy, thermal study and X-ray Rietveld analysis

Cited by 28 publications

References 26 publications

X-ray diffraction and SEM study of kidney stones in Israel: quantitative analysis, crystallite size determination, and statistical characterization

X-ray diffraction and SEM study of kidney stones in Israel: quantitative analysis, crystallite size determination, and statistical characterization

Effect of Diazotated Sulphonated Polystyrene Films on the Calcium Oxalate Crystallization

Type 2 diabetes and uric acid stones: A powder neutron diffraction investigation

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