Structural and optical properties of chitosan–poly(amidoamine) dendrimer composite thin film for potential sensing Pb2+ using an optical spectroscopy

Roshidi, Mohammad Danial Aizad; Fen, Yap Wing; Daniyal, ‬Wan Mohd Ebtisyam Mustaqim Mohd; Omar, Nur Alia Sheh; Zulholinda, Mujawwidin

doi:10.1016/j.ijleo.2019.03.118

Cited by 22 publications

(12 citation statements)

References 43 publications

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“…As powerful analytical tools that have enjoyed widespread attention over the past two decades, SPR sensors have been developed in several configurations to detect several analytes. These sensors serve in different fields such as medical diagnostics [318][319][320][321][322], food quality [323,324], environmental protection [325][326][327][328][329][330][331] and others. SPR, a refractive index-based detection technique has emerged as a promising sensing platform for sensitive detection of NTs, especially DA due to its substantial advantages.…”

Section: Surface Plasmon Resonance Spectroscopymentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Eddin

Fen

2020

Sensors

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Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can change and improve the quality of a patient’s life in addition to reducing the treatment cost. Therefore, the design and development of diagnostic tool for in vivo and in vitro monitoring of DA is of considerable clinical and pharmacological importance. In recent decades, a large number of techniques have been established for DA detection, including chromatography coupled to mass spectrometry, spectroscopic approaches, and electrochemical (EC) methods. These methods are effective, but most of them still have some drawbacks such as consuming time, effort, and money. Added to that, sometimes they need complex procedures to obtain good sensitivity and suffer from low selectivity due to interference from other biological species such as uric acid (UA) and ascorbic acid (AA). Advanced materials can offer remarkable opportunities to overcome drawbacks in conventional DA sensors. This review aims to explain challenges related to DA detection using different techniques, and to summarize and highlight recent advancements in materials used and approaches applied for several sensor surface modification for the monitoring of DA. Also, it focuses on the analytical features of the EC and optical-based sensing techniques available.

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Section: Surface Plasmon Resonance Spectroscopymentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Eddin

Fen

2020

Sensors

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“…An optical-based sensing method based on surface plasmon resonance (SPR) was designed to identify the potential of the Cs/Fe 2 O 3 thin film to detect Hg 2+ . Figure 1 shows the schematic diagram of the SPR instrument setup [58][59][60][61]. The SPR experiment was carried out by inserting Hg 2+ solutions with different concentration varied from 0.01 to 0.5 ppm.…”

Section: Instrumentalmentioning

confidence: 99%

Nanostructured Chitosan/Maghemite Composites Thin Film for Potential Optical Detection of Mercury Ion by Surface Plasmon Resonance Investigation

et al. 2020

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In this study, synthesis and characterization of chitosan/maghemite (Cs/Fe2O3) composites thin film has been described. Its properties were characterized using Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM) and ultraviolet-visible spectroscopy (UV-Vis). FTIR confirmed the existence of Fe–O bond, C–N bond, C–C bond, C–O bond, O=C=O bond and O–H bond in Cs/Fe2O3 thin film. The surface morphology of the thin film indicated the relatively smooth and homogenous thin film, and also confirmed the interaction of Fe2O3 with the chitosan. Next, the UV-Vis result showed high absorbance value with an optical band gap of 4.013 eV. The incorporation of this Cs/Fe2O3 thin film with an optical-based method, i.e., surface plasmon resonance spectroscopy showed positive response where mercury ion (Hg2+) can be detected down to 0.01 ppm (49.9 nM). These results validate the potential of Cs/Fe2O3 thin film for optical sensing applications in Hg2+ detection.

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“…Surface plasmon resonance (SPR) sensing. SPR measurements were conducted based on Kretschmann configuration [65][66][67][68] by evaporating Au/DSU/NH 2 rGO-PAMAM/IgM sensor film onto the prism surface. The prism was placed on an optical stage driven by a stepper motor with a resolution of 0.001° (Newport MM 3000) to let the incident light from laser beam (632.8 nm, 5 mW) pass through the prism and hits a gold layer to generate the surface plasmon waves at the interface.…”

mentioning

confidence: 99%

Sensitive Detection of Dengue Virus Type 2 E-Proteins Signals Using Self-Assembled Monolayers/Reduced Graphene Oxide-PAMAM Dendrimer Thin Film-SPR Optical Sensor

Omar

Fen

Abdullah

et al. 2020

Sci Rep

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123

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In this work, sensitive detection of dengue virus type 2 E-proteins (DENV-2 E-proteins) was performed in the range of 0.08 pM to 0.5 pM. The successful DENV detection at very low concentration is a matter of concern for targeting the early detection after the onset of dengue symptoms. Here, we developed a SPR sensor based on self-assembled monolayer/reduced graphene oxide-polyamidoamine dendrimer (SAM/NH 2 rGO/PAMAM) thin film to detect DENV-2 E-proteins. Surface characterizations involving X-ray diffraction (XRD) and Fourier-transform infrared spectroscopy (FTIR) confirms the incorporation of NH 2 rGO-PAMAM nanoparticles in the prepared sensor films. The specificity, sensitivity, binding affinity, and selectivity of the SPR sensor were then evaluated. Results indicated that the variation of the sensing layer due to different spin speed, time incubation, and concentration provided a better interaction between the analyte and sensing layer. The linear dependence of the SPR sensor showed good linearity (R 2 = 0.92) with the lowest detection of 0.08 pM DENV-2 E-proteins. By using the Langmuir model, the equilibrium association constant was obtained at very high value of 6.6844 TM −1 (R 2 = 0.99). High selectivity of the SPR sensor towards DENV-2 E-proteins was achieved in the presence of other competitors. Dengue virus (DENV) is the most common arthropod-borne viral disease that poses a serious global problem. According to World Health Organization (WHO), the dengue virus is the leading cause of death of 22 000, annually. As of today, the need for hospitalization and medical treatment are constantly dense due to the fact that 390 million people in the world are still infected with DENV 1. Its four distinct serotypes (DENV-1. DENV-2, DENV-3, and DENV-4) are capable of causing a range of clinical symptoms ranging from mild fevers to the severe dengue haemorrhagic fever (DHF) and be potentially life-threatening 2-10. Despite its large burden to human health, no effective vaccine and antiviral therapy are available for the virus 11,12. Early treatment for DENV is only by maintaining the body fluid of the patient, as it is critical in fighting the severe symptoms of DENV 13,14. Hence, an early, rapid, and accurate diagnosis at the onset of infection is the demand of the day in the most epidemic settings. Present discoveries in dengue diagnostics that can help in the early diagnosis are targeting the host-virus itself. DENV consists of a single-stranded positive-sense RNA virus that encodes 10 different types of proteins. Seven of

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Structural and optical properties of chitosan–poly(amidoamine) dendrimer composite thin film for potential sensing Pb2+ using an optical spectroscopy

Cited by 22 publications

References 43 publications

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Nanostructured Chitosan/Maghemite Composites Thin Film for Potential Optical Detection of Mercury Ion by Surface Plasmon Resonance Investigation

Sensitive Detection of Dengue Virus Type 2 E-Proteins Signals Using Self-Assembled Monolayers/Reduced Graphene Oxide-PAMAM Dendrimer Thin Film-SPR Optical Sensor

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