Structural and serological studies of the related O-specific polysaccharides of Proteus vulgaris O21 and Proteus mirabilis O48 having oligosaccharide-phosphate repeating units

Abstract

The O-specific polysaccharide chains (O-antigens) of the lipopolysaccharides (LPSs) of Proteus mirabilis O48 and Proteus vulgaris O21 were found to have tetrasaccharide and pentasaccharide repeating units, respectively, interlinked by a glycosidic phosphate. Polysaccharides and an oligosaccharide were derived from the LPSs by various degradation procedures and studied by 1 H and

Natural phosphoglycans containing glycosyl phosphate units: structural diversity and chemical synthesis

“…34 S. boydii type 13 is related distantly to other Shigella forms, but its O-antigen gene cluster has high levels of sequence similarity with Vibrio cholerae gene clusters. 35 Gram-negative bacteria of the genus Proteus are human facultative pathogens, [36][37][38] which frequently cause wound and urinary-tract infections that can result in severe complications (bacteremia, pyelonephritis). H. alvei is an enterobacterial opportunistic pathogen that causes typical nosocomial infections, including enteric, urinary and respiratory tract disorders.…”