Structural characterization and anti-inflammatory activity of alkali-soluble polysaccharides from purple sweet potato

Chen, Hong; Sun, Jian; Liu, Jun; Gou, Yarun; Zhang, Xin; Wu, Xiaonan; Sun, Rui; Tang, Sixue; Qian, Chunlu; Zhang, Nianfeng; Jin, Changhai

doi:10.1016/j.ijbiomac.2019.03.126

Cited by 78 publications

(35 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…39 Another study also found that the alkali-soluble polysaccharide from purple sweet potato signicantly restrained pro-inammatory agents while enhancing anti-inammatory mediators. 40 These results indicated that WPSPP-1 had potential in vivo anti-inammatory activity.…”

Section: 4mentioning

confidence: 82%

Anti-inflammatory activity of a water-soluble polysaccharide from the roots of purple sweet potato

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

Section: 4mentioning

confidence: 82%

Anti-inflammatory activity of a water-soluble polysaccharide from the roots of purple sweet potato

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…It also contains phenolic acids, anthocyanins and polyphenols, which have anti-inflammatory activity [94]. Its polysaccharide also has anti-inflammatory properties [95,96].…”

Section: Sweet Potatomentioning

confidence: 99%

Food and Food Groups in Inflammatory Bowel Disease (IBD): The Design of the Groningen Anti-Inflammatory Diet (GrAID)

Campmans-Kuijpers

Dijkstra

2021

Nutrients

View full text Add to dashboard Cite

Diet plays a pivotal role in the onset and course of inflammatory bowel disease (IBD). Patients are keen to know what to eat to reduce symptoms and flares, but dietary guidelines are lacking. To advice patients, an overview of the current evidence on food (group) level is needed. This narrative review studies the effects of food (groups) on the onset and course of IBD and if not available the effects in healthy subjects or animal and in vitro IBD models. Based on this evidence the Groningen anti-inflammatory diet (GrAID) was designed and compared on food (group) level to other existing IBD diets. Although on several foods conflicting results were found, this review provides patients a good overview. Based on this evidence, the GrAID consists of lean meat, eggs, fish, plain dairy (such as milk, yoghurt, kefir and hard cheeses), fruit, vegetables, legumes, wheat, coffee, tea and honey. Red meat, other dairy products and sugar should be limited. Canned and processed foods, alcohol and sweetened beverages should be avoided. This comprehensive review focuses on anti-inflammatory properties of foods providing IBD patients with the best evidence on which foods they should eat or avoid to reduce flares. This was used to design the GrAID.

show abstract

“…Inhibition of MAPK and NF -kB signalling pathway was shown by brown alga Sargassum cristaefolium when its polysaccharide was investigated on LPS-stimulated RAW264.7 120 .…”

Section: Immunomodulators From Marine Sourcesmentioning

confidence: 99%

Immunomodulatory Activity of Natural Polysaccharides in Combating Covid -19, Cancer, Inflammatory Disorders: A Review

Priyanka¹,

Chatterjee²,

Saha³

2020

Int J Pharma Bio Sci

View full text Add to dashboard Cite

Natural polysaccharides are a source of carbohydrates with potent biological functions that can be explored for increasing its utilization in the field of food and medicine. If characterized, studied and explored, they would have a vital contribution in the health care policy of the world, and more particularly in numerous developing countries in the next decades. There are thousands of polysaccharides isolated from various natural sources which can affect the immune system by stimulating the immune response or by influencing the formation of antibodies. They consist of various monomer units such as β-glucan, mannan, arabinose, galacturonic acid, fucoidan, laminarin, carrageenan etc. These polysaccharides follow different mechanisms to show the desired biological activity. This review presents a detailed account of the immunomodulatory properties of polysaccharides isolated from microorganisms, plants and marine sources. The outbreak of the novel coronavirus disease COVID-19 which is caused by the SARS-COV-2provide full description of SARS-COV-2 virus has been a serious threat to public health as there are no clinically significant vaccines yet produced for its prevention. Polysaccharide with good immunomodulator and antivirus activity have potent anti-coronavirus applications. This study focuses on the advancements in the inhibition of SARS-COV-2 virus responsible for COVID-19. It also gives a detailed account of the anti-cancer activity of various natural polysaccharides and anti-inflammatory effects. The established therapy strategy for the treatment of cancer and inflammatory disorders involves the use of various chemotherapeutic agents and non-steroidal anti-inflammatory drugs respectively, which have prominent side effects. Polysaccharides obtained from natural sources have gained attention owing to their safety and less side effects. The mechanism of action of the polysaccharides showing immunomodulatory activity owing to treatment of COVID-19, cancer and inflammatory disorders has been discussed in the review. Most polysaccharides are tested using preclinical animal models or by clinical trials. This review will provide guidelines for the development of new formulations for utilising the various biological activity of the natural polysaccharides.

show abstract

Structural characterization and anti-inflammatory activity of alkali-soluble polysaccharides from purple sweet potato

Cited by 78 publications

References 35 publications

Anti-inflammatory activity of a water-soluble polysaccharide from the roots of purple sweet potato

Anti-inflammatory activity of a water-soluble polysaccharide from the roots of purple sweet potato

Food and Food Groups in Inflammatory Bowel Disease (IBD): The Design of the Groningen Anti-Inflammatory Diet (GrAID)

Immunomodulatory Activity of Natural Polysaccharides in Combating Covid -19, Cancer, Inflammatory Disorders: A Review

Contact Info

Product

Resources

About