Structural Fixation of Spontaneous Vesicles in Aqueous Mixtures of Polymerizable Anionic and Cationic Surfactants

Abstract

Two polymerizable surfactants, cationic methacryloyloxyundecyl trimethylammonium bromide and anionic sodium 4-(ω-methacryloyloxyundecyl)oxy benzene sulfonate, have been synthesized. The microstructures formed by mixtures of these surfactants in aqueous solution include stable vesicles, the structure of which can be fixed by polymerization. Both native and polymerized vesicles are characterized using quasi-elastic and static light scattering, small-angle neutron scattering, and cryogenic transmission electron microscopy. Polymerization captures the bilayer structure without creating appreciable intervesicle cross-linking.

A Green Approach for the Synthesis of Fluorescent Polymer Particles by Combined Use of Enzymatic Miniemulsion Polymerization with Clickable Surfmer and Click Reaction

“…11-bromoundecyl methacrylate [33] and N,N-dimethylpropargylamine were reacted under 60 °C for 5 hours, and 1 was obtained in ca. 97% yield.…”

Pharmaceutical applications for catanionic mixtures

“…Both single-chain amphiphiles (Hirano et al 1991;Morgan et al 1997;Chung & Chung 2002;Chung et al 2004a) and multichain amphiphiles have been polymerized (Chung & Chung 2002;Chung et al 2003bChung et al , 2004a. Polymerization can be achieved either by having an amphiphile containing a polymerizable group (Hirano et al 1991;Chung & Chung 2002;Chung et al 2003bChung et al , 2004aLiu et al 2003), or by the addition of separate polymerizable monomers within the surfactant bilayer (Morgan et al 1997). The latter technique has mainly been used to produce hollow polymer spheres (McKelvey et al 2000;McKelvey & Kaler 2002), which will be presented below.…”

New observation of near-reversible behaviors for the redox couple in vesicular solution

“…When cationic surfactant solution and anionic one are simply mixed, the strong reduction in area per head group resulting from ion pairing induces formation of molecular bilayers at low concentrations. At the right mixing ratios vesicles may be established spontaneously and are thermodynamically stable species [10][11][12][13][14][15][16][17][18].…”