Structural, mechanical, and in vitro characterization of freeze-cast scaffolds prepared using a sol-gel-derived bioactive glass from the SiO2–CaO–Na2O–P2O5–K2O–MgO system

Polymeric barrier membranes are used in periodontal applications to prevent fibroblastic cell migration into the cavities of bone tissue and to properly guide the proliferation of tissues. In this study, the fabrication, characterization, bioactivity, and in vitro biological properties of polyvinyl alcohol‐based nanofibrous membranes containing nano‐sized 45S5 bioactive glass (BG) loaded with chlorhexidine (CH) gluconate with biocompatible, bioactive, and antibacterial properties for using as dental barrier membranes were investigated. Nanofibrous membranes with an average fiber diameter, pore size, and porosity of 210 nm, 24.73 μm, and 12.42%, respectively, were loaded with 1% and 2% CH, and the release profile was investigated. The presence of BG in the membranes promoted fibroblastic proliferation and the presence of CH provided antibacterial properties. Nanofibrous membranes exhibit a high ability to restrict bacterial growth while fulfilling the necessary conditions for use as a dental barrier thanks to their low swelling rates, significant surface bioactivities, and appropriate degradation levels.

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Fabrication and characterization of chlorhexidine gluconate loaded poly(vinyl alcohol)/45S5 nano‐bioactive glass nanofibrous membrane for guided tissue regeneration applications

Keçeciler‐Emir

Elalmış

Şahin

et al. 2023

Biopolymers

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Sol–gel‑templated bioactive glass scaffold: a review

Shoushtari,

Hoey,

Biak

et al. 2024

Res. Biomed. Eng.

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Purpose This review paper explores diverse synthesis strategies within the sol–gel technique for producing silicate bioglass with a focus on tailoring these materials for bone scaffold design. Method A comprehensive search was conducted across various databases, including ScienceDirect, Taylor & Francis, PubMed, Hindawi, Royal Society of Chemistry (RSC), Wiley Online Library, ResearchGate, and Google Scholar, using keywords such as “silica bioglass,” “Sol–gel technique,” “Templating,” and “Bone scaffold.” The analysis considered variables such as the sol–gel method, the templating approach, and materials used to fabricate silica bioglass bone scaffolds. Out of 140 initially identified studies, 92 were selected for detailed review published within the last two decades. Result and conclusion In this study, the effect of the sol–gel fabrication technique on the improvement of the structure of silicate bioglass bone scaffolds has been reviewed, along with a consideration of the associated advantages and disadvantages. Specifically, the focus of this study was on the templating sol–gel method and its direct impact on morphology and pore structures. Consequently, these findings have evaluated the development of templating sol–gel fabrication techniques for enhancing the bioactivity and biocompatibility of bone scaffolds.

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Non-isothermal crystallization kinetics for CaO–SrO–B2O3–Al2O3–Bi2O3–SiO2 glass system with Ta2O5 addition

Catalbas,

Basaran,

Selli

2024

Ceramics International

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Structural, mechanical, and in vitro characterization of freeze-cast scaffolds prepared using a sol-gel-derived bioactive glass from the SiO2–CaO–Na2O–P2O5–K2O–MgO system

Cited by 4 publications

References 63 publications

Fabrication and characterization of chlorhexidine gluconate loaded poly(vinyl alcohol)/45S5 nano‐bioactive glass nanofibrous membrane for guided tissue regeneration applications

Fabrication and characterization of chlorhexidine gluconate loaded poly(vinyl alcohol)/45S5 nano‐bioactive glass nanofibrous membrane for guided tissue regeneration applications

Sol–gel‑templated bioactive glass scaffold: a review

Non-isothermal crystallization kinetics for CaO–SrO–B2O3–Al2O3–Bi2O3–SiO2 glass system with Ta2O5 addition

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