Structural modification of olibergin A, an isoflavonoid, from <i>Dalbergia stipulacea</i> Roxb. and its cytotoxicity

Arthan, Supakorn; Posri, Priyapan; Walunchapruk, Sookkawath; Senawong, Thanaset; Yenjai, Chavi

doi:10.1039/d2ra02865d

RSC Adv.

2022

DOI: 10.1039/d2ra02865d

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Structural modification of olibergin A, an isoflavonoid, from Dalbergia stipulacea Roxb. and its cytotoxicity

Supakorn Arthan

Priyapan Posri

Sookkawath Walunchapruk

et al.

Abstract: Fifteen derivatives were synthesized from olibergin A, a major isoflavonoid isolated from the stems of Dalbergia stipulacea Roxb.

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2024

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Cited by 3 publications

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Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Selepe

2024

ChemMedChem

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Isoflavones are phenolic natural compounds with a C6C3C6 framework. They possess a plethora of biological activities that are associated with putative benefits to human health. In particular, the cancer chemopreventive and chemotherapeutic potential of isoflavones has attracted the interest of researchers. Several isoflavone derivatives have been synthesised and probed for their anticancer activities. The isoflavone analogues are mainly synthesised by molecular hybridisation and other strategies that enable diversification through early or late‐stage functionalisation of A‐, B‐ and C‐rings of the isoflavones. This has resulted in the discovery of isoflavone analogues with improved antiproliferative activities against several cancer cells and different mechanisms of action. In this review, the synthesis of isoflavone derivatives and their anticancer activity studies are discussed.

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Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Selepe

2024

ChemMedChem

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Cyclodextrin incorporated textile supercapacitor/piezo-triboelectric nanogenerator hybrid system for versatile temperature dependent wearable wireless devices

Selvam,

Praveenkumar,

Yim

2024

Chemical Engineering Journal

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Unveiling phytochemicals and antioxidant, cytotoxic, anti-thrombotic, anti-inflammatory, and antibacterial activities from the leaves of Dalbergia stipulacea (Roxb.)

Hossain,

Amee,

Hossen

et al. 2024

Pharmacological Research - Natural Products

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Structural modification of olibergin A, an isoflavonoid, from Dalbergia stipulacea Roxb. and its cytotoxicity

Abstract: Fifteen derivatives were synthesized from olibergin A, a major isoflavonoid isolated from the stems of Dalbergia stipulacea Roxb.

Cited by 3 publications

References 23 publications

Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Isoflavone Derivatives as Potential Anticancer Agents: Synthesis and Bioactivity Studies

Cyclodextrin incorporated textile supercapacitor/piezo-triboelectric nanogenerator hybrid system for versatile temperature dependent wearable wireless devices

Unveiling phytochemicals and antioxidant, cytotoxic, anti-thrombotic, anti-inflammatory, and antibacterial activities from the leaves of Dalbergia stipulacea (Roxb.)

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