Structural modulation of heterometallic metal–organic framework via a facile metal-ion-assisted surface etching and structural transformation

Bimetallic Cu–Zn Zeolitic Imidazolate Frameworks as Peroxidase Mimics for the Detection of Hydrogen Peroxide: Electrochemical and Spectrophotometric Evaluation

“…The white colored ZIF-8 powder prepared as above was used for the synthesis of Cu@ZIF-8 . Two different concentrations of copper nitrate hexahydrate solutions (0.03 mM and 1 mM) were prepared in ethanol solvent.…”

“…High surface area, tunable porosity, thermal and chemical stability, biocompatibility, and unique surface topology are the major characteristics of these coordination networks which enable their utilization in various applications like biosensing, catalysis, gas separation, drug delivery, etc . There are several reports on using MOFs as enzyme mimicking materials. ,− Mostly MOFs based on Fe, Cu, Ce, Zr, etc. are found to exhibit the enzyme mimicking properties .…”

“…But ZIF-8 alone cannot mimic the properties of the peroxidase enzyme. However, it is observed that ZIF-8 doped with Cu displays the peroxidase mimicking property . Hence, the Cu-doped bimetallic ZIF-8 (Cu@ZIF-8) is used for dual mode detection of H 2 O 2 both spectrophotometrically as well as electrochemically.…”

“… 9 There are several reports on using MOFs as enzyme mimicking materials. 6 , 10 − 12 Mostly MOFs based on Fe, Cu, Ce, Zr, etc. are found to exhibit the enzyme mimicking properties.…”

“…However, it is observed that ZIF-8 doped with Cu displays the peroxidase mimicking property. 10 Hence, the Cu-doped bimetallic ZIF-8 (Cu@ZIF-8) is used for dual mode detection of H 2 O 2 both spectrophotometrically as well as electrochemically. In this work an attempt has been made to electrochemically sense H 2 O 2 in the presence of the chromogenic substrate, which acts as a mediator, and Cu@ZIF-8, which acts as the peroxidase mimicking material, and this method exactly mimics the colorimetric procedure.…”