Structural Sequelae and Refractive Outcome After Successful Laser Treatment for Threshold Retinopathy of Prematurity

Abstract

The study revealed various structural sequelae and their correlation with refractive outcome.

Refractive errors after the use of bevacizumab for the treatment of retinopathy of prematurity: 2-year outcomes

“…9,10,17 Our study and other case series found a lower SE in patients treated with IVB than in patients treated with cryotherapy (range, À 6.5 to À 3.51 D) or with laser peripheral ablative therapy (range, À 4.71 to À 1.50 D). [3][4][5][6][7] Our prevalences of myopia and high myopia are also similar to those of preschool-age patients in a recent case series who were treated with IVB only (55.6% and 11.1 to 17.0%) ( Table 3). 9,10,17 In the current study, the prevalences of myopia and high myopia increased significantly with the severity of ROP but were not associated with AXL changes.…”

“…The reported rates range from 55.2 to 80.4% and 23.9 to 31.5%, respectively (Table 3). 3,4,6 The reported rates of myopia and high myopia were even higher in patients treated with cryotherapy, ranging from 82.9 to 92.0% and 32.0 to 52.5%, respectively (Table 3). [5][6][7] In the current study, the percentages of patients with myopia and high myopia among IVB-treated patients were 47.5 and 10.0%, respectively, which are less than the previously reported percentages for patients treated with laser treatment or cryotherapy.…”

“…2 However, many investigators have reported high prevalences of myopia and high myopia in preschool-and school-age children who received ablative therapy. [3][4][5][6][7] For these patients, it has been reported that laser treatment for severe ROP results in less myopia than cryotherapy. 6 In the last several years, anti-vascular endothelial growth factor (VEGF) agents have emerged as a new treatment for ROP, and promising experiences have been reported.…”

Evaluation of 2-year outcomes following intravitreal bevacizumab (IVB) for aggressive posterior retinopathy of prematurity

“…Laser treatment has been well-described as a cause of advanced refractive errors in severe cases of ROP (27,28) . Conversely, studies have reported IVB treatment leads to lower degrees of myopic refraction than laser ablation.…”

“…Anisometropia and strabismus are the predominant risk factors for the development of amblyopia in children following laser ablation for severe ROP (28)(29)(30) . The present study demonstrated significantly higher rates of refractive anisometropia and strabismus following laser treatment compared to IVB monotherapy.…”