Structural Studies on Mutants of HMG CoA Reductase from Pseuodomonas Mevalonii

Abstract

conditions (e.g. stress). TA toxins have a bacteriostatic effect that can lead to cell death if sustained. Although the mechanisms of action for a few TA toxins have been uncovered, the intracellular targets of many others have not been identified. Our latest structural and functional data on such complexes will be presented.