Structural Studies on the Radio-Protective Effect of Lycopene (Tomato Supplementation) Against Hepatic Cellular Injury Induced by Chronic Doses of Gamma Radiation

Abstract

Background and aim: Antioxidants are substances that may protect our bodies against the effects of freeradicals. Free radicals are molecules produced when our body breaks down food, or by environmental exposures like radiation. Free radicals can damage cells, our goal of this work is to study the damage resulted by chronic low doses of gamma radiation using natural antioxidant like Lycopene that found in tomato that are available to most of the people especially those that work in the field of radiation.

Protective rules of natural antioxidants against gamma‐induced damage—A review

“…As a result, lycopene would safeguard cellular membrane from lipid peroxidation induced by radiation, thus maintaining the structure of small intestine and inhibiting monoamines release (Saada et al., 2010). Fathy Waer & Shalaby (2012) report demonstrated lycopene effects with dosage of 5 mg/kg daily on adult and healthy male albino rats exposed to radiation of (1/2) Gy. It showed that Lycopene induces great improvement in the cellular organoids structure against cellular damaged induced by the gamma radiation.…”