2021
DOI: 10.1016/j.jinorgbio.2021.111559
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Structural, theoretical and biological activity of mono and binuclear nickel(II) complexes with symmetrical and asymmetrical 4,6-diacetylresorcinol-dithiocarbazate ligands

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Cited by 8 publications
(22 citation statements)
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“…These peaks appeared at m/z = 124, 203 and 235 are due to the fragmentation of the S-benzyldithiocarbazate and the isatin moieties, respectively. The base peak corresponds to the benzyl carbocation which then rearranged to more stable tropylium ion was observed at m/z = 91 [38]. The fragmentation patterns are shown in Scheme 2.…”
Section: Mass Spectrum Analysis Of Hl1mentioning
confidence: 99%
“…These peaks appeared at m/z = 124, 203 and 235 are due to the fragmentation of the S-benzyldithiocarbazate and the isatin moieties, respectively. The base peak corresponds to the benzyl carbocation which then rearranged to more stable tropylium ion was observed at m/z = 91 [38]. The fragmentation patterns are shown in Scheme 2.…”
Section: Mass Spectrum Analysis Of Hl1mentioning
confidence: 99%
“…Nickel has gained prominence in the field of bioinorganic chemistry ( Elsayed et al, 2021 ; Lima et al, 2021 ), as can be seen in recently published works with nickel and dithiocarbazates. Some of these compounds were tested for their cytotoxicity against strains of breast, colon, and liver cancer cells and showed outstanding antitumor activity against breast cancer cells MCF7, inducing cell death by cellular apoptosis.…”
Section: Introductionmentioning
confidence: 99%
“…Considering our interest in developing metal complexes with antitumor potential ( Lima et al, 2021 ; Almeida et al, 2022 ; Cavalcante et al, 2022 ), we describe the synthesis and characterization by single-crystal X-ray diffraction, Hirshfeld surface, FT-IR, UV–Vis, mass spectrometry, and 1 H nuclear magnetic resonance of dithiocarbazate ligands derivated from 1,1,1-trifluoro-2,4-pentanedione and their Ni(II) complexes. In addition, the cytotoxic potential of all compounds against human cancer cell lines was evaluated, and the results were compared to indicate the impact of structural variations on biological activity ( Gu et al, 2019 ; Wang et al, 2019 ; Cavalcante et al, 2022 ).…”
Section: Introductionmentioning
confidence: 99%
“…Due to our interest in the development of metal complexes with antitumoral potential, [ 45–47 ] we describe the synthesis of new organometallic gold (III) and platinum (II) complexes with thiosemicarbazone and the characterization with elemental analysis, spectroscopic techniques, single‐crystal X‐ray diffraction, and Hirshfeld surface. Finally, the complexes were evaluated for biological activity against MCF‐7 human cancer cell line and molecular docking studies.…”
Section: Introductionmentioning
confidence: 99%