Structure and bioactivities of a galactose rich extracellular polysaccharide from submergedly cultured Ganoderma lucidum

Immune-stimulated antitumor effect of different molecular weight polysaccharides fromMonascus purpureuson human leukemic U937 cells

“…Our study showed that the inhibition by a medium size polysaccharide MP3 (50-100 kDa) at 50 μg/ mL reaches 42.2 ± 2.1%. The average molecular mass of purified polysaccharide obtained from Poria cocos is 160 kDa, which exhibited antiproliferative and differentiating effects (Li, Fang, & Zhang, 2007). However, the polysaccharide purified from Ganoderma lucidum with molecular weight of 22 kDa in submerged culture could stimulate the growth of T and B lymphocyte (Li et al, 2007).…”

Ganoderma lucidum Polysaccharides and Terpenoids: Profile and Health Benefits

“…A galactose rich extracellular polysaccharide composed of galactose, mannose, glucose, arabinose and rhamnose in different molar ratios and molecular weight was also isolated and identified in G. lucidum [30,31], and later Pan et al [32] isolated another neutral heteropolysaccharide containing galactose, rhamnose and glucose in mole ratio of 1.00:1.15:3.22, respectively. Other polysaccharides containing xylose, fructose, glucose, sucrose and maltose in different molar ratios were also isolated and identified, and analysis has shown that maltose yielded more than 50% of the total saccharides [33].…”

Bioremediation of Dyes Using Ultrafine Membrane Prepared from the Waste Culture of Ganoderma lucidum with in-situ Immobilization of Laccase

“…The production of ganoderic acid (Fang and Zhong 2002), polysaccharide (Li et al 2007;Liu and Zhang 2007;Ding et al 2012a), enzyme (Ding et al 2012b), and its medical applications (Zhang et al 2011) all have been thoroughly studied. However, all the fermentation culture after each study would be poured out to the sewer, which not only would waste the useful components, but also pollute the environment with its high COD, and the microorganism community in the sewer also would be affected at the same time.…”

“…Nowadays G. lucidum has been used to treat and prevent cancer, immunological disorders, hepatitis, hypertension, and other diseases. Many studies have revealed that G. lucidum extracts can inhibit the growth of many tumor cells such as lung cancer cell, colorectal prostate cancer cells, and breast cancer cells (Li et al 2007;Liu and Zhang 2007;Xu et al 2011). The fruiting body of G. lucidum is made of polysaccharides, terpenoids, amino acids, alkaloids, and proteins, etc.…”

“…lucidum has been used to produce the polysaccharides (Li et al 2007;Liu and Zhang 2007;Ding et al 2012a), ganoderic acid (Xu et al 2008), enzyme (Ding et al 2012b) and so on in the laboratories. However, the culture of G. lucidum is usually drained after its use, no matter what valuable things it may contain or no matter whether it would contaminate the ground water, or affect the microbiology diversity in the water.…”