Structure and Hypotensive Effect of Flavonoid Glycosides in<i>Citrus unshiu</i>Peelings

Matsubara, Yoshiharu; Kumamoto, Hiroyasu; Iizuka, Yoshitomi; Murakami, Tetsuo; Okamoto, Kozo; Miyake, Hideo; Yokoi, Katsumi

doi:10.1080/00021369.1985.10866832

Cited by 24 publications

(16 citation statements)

References 5 publications

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“…Several other compounds, previously identified via UPLC-DAD-MS, were obtained in the pure form and their structural assignment was supported by comparison of experimental NMR data with those reported in the literature: eriocitrin ( 7 ), narirutin ( 8 ), luteolin-6,8-di- C -glucoside ( 11 ), apigenin-6,8-di- C -glucoside ( 12 ), diosmetin-6,8-di- C -glucoside ( 14 ), apigenin-6- C -glucoside ( 16 ), chrysoeriol-8- C -glucoside ( 17 ), diosmetin-8- C -glucoside ( 19 ), rutin ( 24 ), sinensetin ( 25 ), tangeretin ( 26 ), and bergaptene ( 28 ) …”

Section: Results and Discussionsupporting

confidence: 56%

Detailed Phytochemical Characterization of Bergamot Polyphenolic Fraction (BPF) by UPLC-DAD-MS and LC-NMR

Formisano

Rigano

Lopatriello

et al. 2019

J. Agric. Food Chem.

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Bergamot (Citrus bergamia) is cultivated in Southern Italy almost exclusively to produce the prized essential oil, a top note in several perfumes. The juice of bergamot, until recently poorly studied, is the object of a growing scientific interest due to its claimed activity to treat metabolic syndrome. The aim of this investigation was a detailed characterization of bergamot juice polyphenolic fraction (BPF) based on a UPLC-DAD-MS analysis complemented by preparative chromatographic separations, followed by NMR characterization of the isolated compounds. The combination of these techniques efficiently covered different classes of secondary metabolites, leading to the identification of 39 components, several of which had never been reported from bergamot. One of them, bergamjuicin (35), is a new flavanone glycoside, whose structure has been determined by MS and NMR techniques. The reported results could provide a guide for future routine analyses of BPF, a material of great nutraceutical and industrial interest.

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Section: Results and Discussionsupporting

confidence: 56%

Detailed Phytochemical Characterization of Bergamot Polyphenolic Fraction (BPF) by UPLC-DAD-MS and LC-NMR

Formisano

Rigano

Lopatriello

et al. 2019

J. Agric. Food Chem.

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“…20) Hyaluronidase inhibitory activity 21) was measured for these compounds. Caffeic acid oligomers showed strong inhibitory activity similar to rosmarinic acid (9), which was reported to have the strongest activity as a natural product.…”

Section: Resultsmentioning

confidence: 99%

Caffeic Acid Oligomers with Hyaluronidase Inhibitory Activity from <i>Clinopodium gracile</i>

Aoshima

Miyase

Warashina

2012

CHEMICAL & PHARMACEUTICAL BULLETIN

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Eight new caffeic acid oligomers, clinopodic acids J-Q (1-8), were isolated from whole plants of Clinopodium gracile, together with nine known caffeic acid oligomers. The caffeic acid oligomers with two to four dihydrobenzofuran rings were isolated as natural products for the first time. Clinopodic acid M (4) showed the strongest hyaluronidase inhibitory activity, IC 50 (19 µM) among the 22 compounds isolated from this plant.

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“…Thus, of four flavonoid glycosides 59 extracted from orange peel, two decreased the blood pressure of rats. Potentially pharmacologically active agents were also studied 60 in the peel of Citrus unshiu. Flavonoid glycosides were isolated from an aqueous extract of peel by precipitation with ethanol and sequential extraction with hexane and butanol.…”

Section: Properties and Physiological Activity In Animalsmentioning

confidence: 99%

Analytical Chemistry of Fruit BioflavonoidsA Review

Robards¹,

Antolovich²

1997

Analyst

437

267

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Structure and Hypotensive Effect of Flavonoid Glycosides inCitrus unshiuPeelings

Cited by 24 publications

References 5 publications

Detailed Phytochemical Characterization of Bergamot Polyphenolic Fraction (BPF) by UPLC-DAD-MS and LC-NMR

Detailed Phytochemical Characterization of Bergamot Polyphenolic Fraction (BPF) by UPLC-DAD-MS and LC-NMR

Caffeic Acid Oligomers with Hyaluronidase Inhibitory Activity from <i>Clinopodium gracile</i>

Analytical Chemistry of Fruit BioflavonoidsA Review

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