Abstract:Misfolding
and fibrillar aggregation of Aβ is a characteristic
hallmark of Alzheimer’s disease and primarily participates
in neurodegenerative pathologies. There has been no breakthrough made
in the therapeutic regime of Alzheimer’s disease while the
pharmacological interventions against Aβ are designed to sequester
and clear Aβ burden from the neurological tissues. Based on
the physiological relevance of Aβ, therapeutic approaches are
required to inhibit and stabilize Aβ fibrillization, instead
of cleaning it… Show more
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