“…These substrates include ProA, PlaA, Map, PlaC (acetyltransferase), PlcA (phospholipase C), SrnA (ribonuclease), ChiA (chitinase), CelA (cellulase), LapA, LapB (aminopeptidases), and NttA,B,C,D,E,G [ 204 , 209–212 ]. NttA,C,D,E are required for L. pneumophila replication within multiple species of amoebae[ 212 ]. The T2SS substrates LegP and Map contain eukaryotic-like protease motifs [ 204 , 213 ].…”