Structure elucidation and complete NMR spectral assignments of a novel sesquiterpene glycoside from Ixeris sonchifolia

Abstract

A novel sesquiterpene glycoside was isolated from the whole plant of Ixeris sonchifolia. The structure was established as 1(10)E-4Z-3alpha-hydroxy-germacra-1(10),4,11(13)-trien-6, 12-olide-14-O-beta-D-glucopyranoside (1) on the basis of spectroscopic techniques and chemical analysis.

Systematic characterisation of secondary metabolites from Ixeris sonchifolia by the combined use of HPLC‐TOFMS and HPLC‐ITMS

“…Ixeris sonchifolia (Bunge) Hance, also called Kudiezi in Chinese and belonging to the plant family Compositae, has been traditionally used as a folk medicine in China for its anti‐inflammatory and haemostatic effects (Ye et al ., 2007). A few components have been isolated from the plant, including flavonoids and sesquiterpene lactones (Dai et al ., 2006), some of which were reported to possess anti‐inflammatory, anti‐atherosclerotic and anticancer activities (Lu et al ., 2002; Suh et al ., 2002; Yee et al ., 2003).…”