Structure, preparation, modification, and bioactivities of β-glucan and mannan from yeast cell wall: A review

Liu, Yana; Wu, Qin; Wu, Xiangyun; Algharib, Samah Attia; Gong, Fayuan; Hu, Junpeng; Luo, Wanhe; Zhou, Meifang; Pan, Yuanhu; Yan, Yuanyuan; Wang, Yulian

doi:10.1016/j.ijbiomac.2021.01.125

Cited by 112 publications

(60 citation statements)

References 132 publications

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“…In recent years, β-glucans have attracted growing interest as an ingredient in food formulations [ 10 , 11 ] and, in 2011, β-glucans from yeast and fungi were approved by the European Commission as novel food ingredients [ 12 , 13 ]. Several studies have demonstrated the ability of β-glucans to promote the growth and survival of lactic acid bacteria (LAB) [ 14 , 15 , 16 , 17 ]. Similarly, mannan-oligosaccharides (MOS) have the capacity to stimulate the growth of different beneficial lactobacilli species of the intestinal microbiota, both in humans and animals [ 18 , 19 , 20 ].…”

Section: Introductionmentioning

confidence: 99%

Growth-Promoting Effect of Cava Lees on Lactic Acid Bacteria Strains: A Potential Revalorization Strategy of a Winery By-Product

Hernández-Macias

Comas-Basté

Jofré

et al. 2021

Foods

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The growing trend of circular economy has prompted the design of novel strategies for the revalorization of food industry by-products. Cava lees, a winery by-product consisting of non-viable cells of Saccharomyces cerevisiae rich in β-glucans and mannan-oligosaccharides, can be used as a microbial growth promoter, with potential food safety and health applications. The aim of this study was to assess in vitro the effect of cava lees on the growth of 21 strains of lactic acid bacteria (LAB) species commonly used as starter cultures and/or probiotics. Firstly, 5% of cava lees was selected as the most effective amount for enhancing microbial counts. After screening different LAB, statistically significantly (p < 0.05) higher microbial counts were found in 12 strains as a consequence of cava lees supplementation. Moreover, a greater and faster reduction in pH was observed in most of these strains. The growth-promoting effects of cava lees on LAB strains supports the potential revalorization of this winery by-product, either to improve the safety of fermented products or as a health-promoting prebiotic that may be selectively fermented by probiotic species.

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Section: Introductionmentioning

confidence: 99%

Growth-Promoting Effect of Cava Lees on Lactic Acid Bacteria Strains: A Potential Revalorization Strategy of a Winery By-Product

Hernández-Macias

Comas-Basté

Jofré

et al. 2021

Foods

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“…β-Glucan is a polysaccharide with several biological activities with scientifically proven beneficial health effects. Cereal wastes from barley, oats, and residual yeast biomass can also be used as a source of β-glucan (Tosh et al, 2010;Du et al, 2014;Vieira et al, 2017;Guedes et al, 2019;Liu et al, 2021).…”

Section: Bioactive Compoundsmentioning

confidence: 99%

Biological Approaches for Extraction of Bioactive Compounds From Agro-industrial By-products: A Review

Lemes

Egea

Filho

et al. 2022

Front. Bioeng. Biotechnol.

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Bioactive compounds can provide health benefits beyond the nutritional value and are originally present or added to food matrices. However, because they are part of the food matrices, most bioactive compounds remain in agroindustrial by-products. Agro-industrial by-products are generated in large quantities throughout the food production chain and can—when not properly treated—affect the environment, the profit, and the proper and nutritional distribution of food to people. Thus, it is important to adopt processes that increase the use of these agroindustrial by-products, including biological approaches, which can enhance the extraction and obtention of bioactive compounds, which enables their application in food and pharmaceutical industries. Biological processes have several advantages compared to nonbiological processes, including the provision of extracts with high quality and bioactivity, as well as extracts that present low toxicity and environmental impact. Among biological approaches, extraction from enzymes and fermentation stand out as tools for obtaining bioactive compounds from various agro-industrial wastes. In this sense, this article provides an overview of the main bioactive components found in agroindustrial by-products and the biological strategies for their extraction. We also provide information to enhance the use of these bioactive compounds, especially for the food and pharmaceutical industries.

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“…In fungi of the genus Candida, the presence of this GPI anchor is essential for growth, virulence and resistance to macrophages so that different enzymes catalyzing the biosynthesis of the GPI anchor have been proposed as potential antifungal targets. Thus, the inositol acylase encoded by the GwtI gene is one of these targets that were first identified [37] in 2003. The search for an inhibitor of inositol acylase led to the discovery of the compound E1210, which has remarkable antifungal activity in vitro and in vivo.…”

Section: Biosynthesis Of the Anchor Glycosyl Phosphatidy Linositol (Gpi)mentioning

confidence: 99%

New Biological Targets in Fungi and Novel Molecule under Development: A Review

Coulibaly¹,

N'guessan²,

Kacou³

et al. 2021

CSIJ

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Antifungal therapeutics is confronted today with the challenge of drug resistance of most fungal germs to current antifungal drugs. Faced with this situation, the search for new and more efficient antifungal molecules that avoid the phenomenon of drug resistance becomes an urgent task. The design of new antifungal drugs acting on new biological targets and/or by innovative mechanisms of action is essential in the fight against fungal infections. Current advances in molecular biology have identified new targets for the development of new antifungal therapy. Several biological targets for the development of new antifungal agents are currently being explored. Amongst these, the most promising are BET (Bromodomain and Extra-Terminal) proteins, Homoserine transacetylase (HTA), mannan cell wall, Glycosylphosphatidylinositols (GPI) anchor biosynthesis, Histone deacetylases, Sphingolipid biosynthesis, D9 fatty acid desaturase and Chitin biosynthesis. This review summarizes the new biological targets and their inhibitors under development as potential new antifungal drugs.

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Structure, preparation, modification, and bioactivities of β-glucan and mannan from yeast cell wall: A review

Cited by 112 publications

References 132 publications

Growth-Promoting Effect of Cava Lees on Lactic Acid Bacteria Strains: A Potential Revalorization Strategy of a Winery By-Product

Growth-Promoting Effect of Cava Lees on Lactic Acid Bacteria Strains: A Potential Revalorization Strategy of a Winery By-Product

Biological Approaches for Extraction of Bioactive Compounds From Agro-industrial By-products: A Review

New Biological Targets in Fungi and Novel Molecule under Development: A Review

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