Structures, photoresponse properties and DNA binding abilities of 4-(4-pyridinyl)-2-pyridone salts

Abstract

The optical band gap energies in several 2-pyridone derivatives have been measured using solid state UV to explore their semiconductor behavior. The electric current measurements for the four compounds exhibit enhanced photoconduction properties under irradiation of light.

Structures, Photoresponse Properties, and Biological Activity of Dicyano-Substituted 4-Aryl-2-pyridone Derivatives

“…This behavior has been previously described in perovskites 64,65 and in pyridone-based organic salts. 66…”

“…This behavior has been previously described in perovskites 64,65 and in pyridone-based organic salts. 66 The analysis of the optical properties is needed to rationalize the electronic structure of the crystal structure. The computation of the dielectric function ε(ω) and the optical conductivity σ(ω) is convenient to study how frequently the photon is absorbed into the material.…”

“…Figure 14 shows how changes in the concentration of CT-DNA affect the absorption spectra of the compound (2); the absence of any isosbestic point in the spectra may be due to the larger molar extinction coefficient of (2) over that of the compound−DNA complex, formed during binding. 66,68 The binding constant of the compound was determined using the Benesi−Hildebrand plot 67 (Figure 14, inset) and was found to be 9.21 × 10 2 M −1 .…”

Synthesis of Highly Conjugated Functionalized 2-Pyridones by Palladium-Catalyzed Aerobic Oxidative Dicarbonation Reactions of N-(Furan-2-ylmethyl) Alkyne Amides and Alkenes as Coupling Partners

“…Over the past few decades, researchers have developed numerous straightforward and efficient methods for synthesizing molecules with heterocyclic skeletons, including compounds with 2-pyridone moieties, which are prevalent in pharmaceuticals and bioactive natural products (Figure ). Owing to their distinctive structural and electronic properties, 2-pyridones are also widely used for materials science applications . 2-Pyridones are typically synthesized by oxidation of pyridines, but this method usually requires strong oxidants, an acidic medium, or a high temperature, making it unsuitable for molecules with sensitive functional groups.…”

Synthesis of some new Aryl-azo derivatives clubbed with Pyridone and evaluating their Biological Broadcast.

“…Pyridones is considered as one of the heterocyloc moieties with interesting biological activities [7]. Where, 2-pyridone skeleton "dominant tautomer of 2-hydroxypyridine" is correspondingly existent in DNA and RNA particles [8]. Meanwhile, Pyridone analogues have pharmaceutical and an extensive assortment of pharmacological efficacies [9].…”