Studies on a novel bioactive glass and composite coating with hydroxyapatite on titanium based alloys: Effect of γ-sterilization on coating

Bharati, Sanghamitra; Soundrapandian, Chidambaram; Basu, Debabrata; Datta, Someswar

doi:10.1016/j.jeurceramsoc.2009.02.013

Cited by 32 publications

(13 citation statements)

References 54 publications

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“…1). B 2 O 3 was added to all formulations for the trabecular coating on one hand to promote the bioactivity (it is known to increase glass reactivity upon contact with aqueous solutions [28]) and, on the other hand, to reduce the CTE [29], which is a (minor) goal for this application. Tendency to dissolution in biological fluids was employed as the first, key eliminatory criterion for materials selection.…”

Section: Resultsmentioning

confidence: 99%

Design, selection and characterization of novel glasses and glass-ceramics for use in prosthetic applications

Baino

Marshall

Kirk

et al. 2016

Ceramics International

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Section: Resultsmentioning

confidence: 99%

Design, selection and characterization of novel glasses and glass-ceramics for use in prosthetic applications

Baino

Marshall

Kirk

et al. 2016

Ceramics International

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“…HAp may serve not only as a bone filler but also as a carrier of active substances: antibiotics, chemiotherapeutics, growth factors, etc. [4][5][6][7][8][9]; it can also be used in composites, as a factor increasing their cytocompatibility, bioactivity, osteoconductivity, adhesion of coatings and compression modulus [10][11][12][13][14]. On the other hand, HAp application is often limited due to its relatively poor resorption and slow replacement by the host bone after implantation, substantially high Young modulus, and low fracture toughness [15,16], although these properties may be improved by addition of elasticity-increasing polymers.…”

Section: Introductionmentioning

confidence: 99%

Application of β-1,3-glucan in production of ceramics-based elastic composite for bone repair

et al. 2013

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Application of β-1,3-glucan in production of ceramics-based elastic composite for bone repair IntroductionHydroxyapatite (HAp), especially in a porous form, is appreciated as a bone filler due to its biocompatibility, bioactivity, osteoconductivity, minimal risk of appearance of allergic reactions, lack of carcinogenic properties and lack of sensitivity to sterilization processes [1][2][3]. There are numerous commercially available bone graft materials based on biologic and synthetic HAp, including ProOsteon ® (Interpore Cross International, USA), Endobon (BIOMET Orthopaedics, Switzerland), Cerapatite (Ceraver Osteal, France), Synatite (SBM, France) and others. HAp may serve not only as a bone filler but also as a carrier of active substances: antibiotics, chemiotherapeutics, growth factors, etc. [4][5][6][7][8][9]; it can also be used in composites, as a factor increasing their cytocompatibility, bioactivity, osteoconductivity, adhesion of coatings and compression modulus [10][11][12][13][14]. On the other hand, HAp application is often limited due to its relatively poor resorption and slow replacement by the host bone after implantation, substantially high Young modulus, and low fracture toughness [15,16], although these properties may be improved by addition of elasticity-increasing polymers. It is considered that polymer-ceramic composites reveal superior properties (at least in some aspects) over polymer and ceramic alone [17]. However, most polymers used for bone filler fabrication meet only some of the criteria for implantable materials.Bone replacing material such as ceramics or crushed bone offers an insufficient surgical handiness, especially when the orthopedic surgeon has to handle granules (in case of defects in maxillary bone) or scaffolds (rigid and non-adaptable to the implantation site). Some commercially available biomaterials contain the artificial or natural polymers serving as plasticizing agents and thus significantly reduce this inconvenience. Among them, EasyGraft TM (Degradable Solutions SA, Switzerland), Plexur M and P (Osteotech, USA) and Cerapatite-Collagen (Ceraver Osteal, France) can be listed. EasyGraft TM contains PLGA-coated β-TCP granules which hardens into a compact mass via partial and temporary PLGA dissolution by organic solvent; Plexur M and P are composed of cortical bone and resorbable artificial polymer; Cerapatite-Collagen, made from HAp granules and naturally-derived collagen fibers, becomes elastic after hydration with blood or saline. Bone or ceramic granules and powders may also be turned into a paste using collagen gels (e.g., Tecnoss ® Gel O; Tecnoss, Italy) or fibrin glue [18,19]. However, the natural polymeric compounds used in commercially available composites (collagen, fibrin glue) originate from animal sources; this can be considered as a limiting factor because of the increased risk of transmissible contamination (e.g. viruses) and undesirable immune responses. Thus, the necessity of careful purification of these animal polymers exacts the high price of fin...

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“…As an alternative, creating a multi-layered system or a functionally graded coating with smooth change in composition and thermomechanical properties may be applied [25,26]. The use of nanosized additives, instead of micrometric HA powders, or γ-rays sterilisation are another ways to improve the performance of the composite coatings [24]. A list of relevant papers summarising different enamelled bioactive glass coatings is provided elsewhere [7].…”

Section: Bioactive Glasses Glass-ceramics and Implant Coating Technimentioning

confidence: 99%

3D analysis of thermal and stress evolution during laser cladding of bioactive glass coatings

Krzyżanowski

Bajda

Liu

et al. 2016

Journal of the Mechanical Behavior of Biomedical Materials

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Thermal and strain-stress transient fields during laser cladding of bioactive glass coatings on the Ti6Al4V alloy basement were numerically calculated and analysed. Conditions leading to micro-cracking susceptibility of the coating have been investigated using the finite element based modelling supported by experimental results of microscopic investigation of the sample coatings. Consecutive temperature and stress peaks are developed within the cladded material as a result of the laser beam moving along the complex trajectory, which can lead to micro-cracking. The preheated to 500°C base plate allowed for decrease of the laser power and lowering of the cooling speed between the consecutive temperature peaks contributing in such way to achievement of lower cracking susceptibility. The cooling rate during cladding of the second and the third layer was lower than during cladding of the first one, in such way, contributing towards improvement of cracking resistance of the subsequent layers due to progressive accumulation of heat over the process.

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Studies on a novel bioactive glass and composite coating with hydroxyapatite on titanium based alloys: Effect of γ-sterilization on coating

Cited by 32 publications

References 54 publications

Design, selection and characterization of novel glasses and glass-ceramics for use in prosthetic applications

Design, selection and characterization of novel glasses and glass-ceramics for use in prosthetic applications

Application of β-1,3-glucan in production of ceramics-based elastic composite for bone repair

3D analysis of thermal and stress evolution during laser cladding of bioactive glass coatings

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