Studies on Lipid Profile Levels in Hypertensive and Type 2 Diabetes Mellitus

Abstract

Studies on the effect of non-hypertensive and hypertensive type 2 diabetes on lipid profile was performed to determine whether these biochemical parameters were affected in individuals associated with these disease conditions. A total of one hundred and thirty-three (133) individuals were used for these studies. Of these thirty-five (35) were established hypertensive diabetics and thirty (30) are established non-hypertensive diabetics. The established hypertensive non-diabetics were thirty-three (33) while thirty-five (35) were normal healthy individuals. The results showed that there was no significant differences (P>0.05) in the mean concentrations of cholesterol, triglycerides, HDL-cholesterol, LDLcholesterol and glucose between hypertensive diabetics and non-hypertensive diabetics studied. The study also showed that there were no significance differences (P>0.05) in the mean levels of all the parameters measured between hypertensive diabetics and hypertensive non-diabetics subjects studied, except for serum glucose that significantly higher (P<0.05) in hypertensive diabetics. It was observed that mean concentrations of cholesterol, triglycerides, LDC-cholesterol, as well as systolic blood pressure were significantly higher (P<0.05) in hypertensive diabetics compared with normal healthy individuals. The results also show that the mean HDL-cholesterol level was significantly lower (P>0.05) in hypertensive diabetics compared with normal healthy individuals. It was also observed that the concentrations of cholesterol, triglycerides, LDL-cholesterol systolic and diastolic blood pressure were significantly higher (P>0.05) in hypertensive non diabetics individuals compared with normal healthy individuals studied. However, the glucose and pulse rate mean levels showed no significant difference (P>0.05) between hypertensive non-diabetics and normal healthy individuals.