Studies on Some Plant Extracts for Their Antimicrobial Potential against Certain Pathogenic Microorganisms

Sheikh, Muzafar; Malik, Abdul; Meghavanshi, M. K.; Mahmood, Irshad

doi:10.4236/ajps.2012.32025

Cited by 25 publications

(18 citation statements)

References 9 publications

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“…However, the efficacy is low at approximately 11% (Table 4, Figure 1C and 1D). The efficacy of the Ageratum leaf extract is reported by previous researchers [7,16]. The inhibition zone observed when the aqueous Ageratum extract was administered is 8.33 mm at 48 hours on Aspergillus [16].…”

Section: Efficacy Of Ageratum Extract On Chilli Fruits After Inoculatmentioning

confidence: 63%

“…The efficacy of the Ageratum leaf extract is reported by previous researchers [7,16]. The inhibition zone observed when the aqueous Ageratum extract was administered is 8.33 mm at 48 hours on Aspergillus [16]. Hidangmayum and Singh [7] show that the in vitro efficacy of the 5% and 20% Ageratum extract is 1.83% and 14.29%, respectively.…”

Section: Efficacy Of Ageratum Extract On Chilli Fruits After Inoculatmentioning

confidence: 80%

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EFFICACY OF Ageratum LEAF EXTRACT ON POSTHARVEST ROT CAUSED BY Aspergillus niger AND Colletotrichum sp. ON CHILLI FRUITS

Toàn¹,

Linh²,

Bao³

2019

HueUni-JARD

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Abstract: The damage of chilli, an important spice fruit, comes from fungal diseases caused mainly by Aspergillus niger and Colletotrichum sp. The fungi on chilli fruits would directly harm consumers’ health. Plant extracts containing bio-active compounds with antimicrobial properties could be a good possible solution to deal with the fungi. This study aims to evaluate the in vitro and in vivo efficacy of aqueous extracts from the leaves of Ageratum plants against A. niger and Colletotrichum sp. The results show that the optimal efficacy of the treatment of Ageratum leaf extract is at a concentration of 6%, with the efficacy of Ageratum leaf extract on colonial diameter at approximately 43–44% for the two fungi at 96 hours after inoculation. The 6% Ageratum leaf extract has a high efficacy (~54.23%) on limiting the development of Aspergillus rot lesions on chilli fruits 4 days after inoculation. Meanwhile, the efficacy of the extract on Colletotrichum lesions is 11.34%, lower than that of Aspergillus rot.Keywords: Ageratum leaf extract, chilli fruit, rot lesion

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Section: Efficacy Of Ageratum Extract On Chilli Fruits After Inoculatmentioning

confidence: 63%

Section: Efficacy Of Ageratum Extract On Chilli Fruits After Inoculatmentioning

confidence: 80%

EFFICACY OF Ageratum LEAF EXTRACT ON POSTHARVEST ROT CAUSED BY Aspergillus niger AND Colletotrichum sp. ON CHILLI FRUITS

Toàn¹,

Linh²,

Bao³

2019

HueUni-JARD

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“…Secondly, that the treated animals' leucocytic parameters remained low even after twenty eight days may as well imply that other than inhibition of immune stimulatory factors, the extract may have protected the animals against microbial infections. This was attributed to the exemplary antimicrobial activity of Prosopis juliflora leaf extracts as reported by several researchers [3,8].…”

Section: Discussionmentioning

confidence: 95%

Evaluation of In Vivo Toxicity of Dichloromethane: Methanolic Leaf Extracts of Prosopis juliflora in Female Wistar Albino Rats

KO¹,

DW²

2015

J Drug Metab Toxicol

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Prosopis juliflora (Mathenge) is an exotic, evergreen leguminous plant found in the dry Coastal, Rift Valley and Northern parts of Kenya. It is tolerant to extreme environmental conditions, rated among top 100 most invasive species worldwide. The species leaf extracts is used in folk cure to various ailments and have promising pharmacological properties however; information on their toxicity in animals and human is insufficient. The study assessed phytochemical composition of P. juliflora leaf extracts, effects on body weights, organ weights, hematological parameters, liver function markers and histopathology in major organs of Wistar albino rats. Acute toxicity test was carried out at 2000 mg/kg body weight followed by a 28 days sub chronic toxicity study at 100, 350 and 1000 mg/kg body weight extracts dosages. The control animals were administered with normal saline. Animals were monitored for physical and behavioral changes including death. They were fasted overnight on 28th day and sacrificed on anesthesia on 29th day. Blood was collected by cardiac puncture. Hematological and liver functions tests were done. Tissue sample of selected organs were processed for histopathology. Data from control and treated animals groups were analyzed by ANOVA and Dunnett's test. Phytochemicals confirmed included alkaloids, flavonoids, phenols, tannins, terpenoids and saponnins but no cardiac glycosides. Median lethal dose was estimated at above 2000 mg/kg body weight. Dose related transient toxicity symptoms included wheezing, decreased activity, and pilo erection. No significant toxicity effects on hematological parameters were noticed except in mean platelets volume. Similarly, no significant adverse effects occurred in liver function tests except at 1000 mg/kg body weight dosage. No significant adverse changes in plasma proteins, body weights and absolute organ weights were observed except in kidneys and spleen. Histological examination of sample tissues showed mild effects in spleen and kidneys but no adverse pathology in other organ tissues.

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“…However, environment and health issue has been arising, thereby becoming a public concern that needs to be considered. An alternative way to suppress the growth of food spoilage fungi needs to be discovered (Sheikh et al, 2012). Currently, the natural antifungal from plants extracts become an alternative (Cabral et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Antifungal activity of Piper cubeba L. extract on spoilage fungi isolated from tomato, grapes and lemon

Fazly-Ann¹,

Nor-Hafizah²,

Rukayadi³

2019

Food Res.

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The berries of Piper cubeba L. or commonly recognized as tailed pepper are traditionally used as flavoring ingredients in various types of food. It has been reported with abundant of phytochemical compounds that contribute to its nutritional and medicinal properties. The antimicrobial effect of the spice including antifungal activity was believed to reduce the potential of fungal spoilage thus minimizing food losses and wastage. This study was aimed to determine the antifungal activity of P. cubeba L. extract against isolated spoilage fungi namely Geotricum candidum (TMa 001), Penicillium citrinum (GRd 001) and Trametes hirsuta (LMd 001) by in vitro and in vivo techniques. Disc diffusion assay, minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) test of the methanolic extract were performed on the selected fungi. The largest inhibition zone, fungistatic and fungicidal effects were detected in T. hirsuta with 18.30±3.00 mm, 0.039 mg/mL and 0.078 mg/mL, respectively. The inhibition of conidial germination assay was performed at 0 × MIC, 0.5 × MIC, 1 × MIC, 2 × MIC, and 4 × MIC, and the result showed G. candidum were completely inhibited at 4 × MIC. The ideal concentration of P. cubeba L. extract on different selected food commodities were 0.50% against G. candidium in tomato, 0.50% to 5.00% against P. citrinum in grapes, and 5.00% against T. hirsuta in lemon. The findings implied that P. cubeba L. extract can be listed as one of the natural antifungal agents in food. The availability of various types of natural antifungal agents will help in reducing the usage of chemical fungicide, which may lead to adverse and deteriorating health effects in the events of prolong consumption.

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Studies on Some Plant Extracts for Their Antimicrobial Potential against Certain Pathogenic Microorganisms

Cited by 25 publications

References 9 publications

EFFICACY OF Ageratum LEAF EXTRACT ON POSTHARVEST ROT CAUSED BY Aspergillus niger AND Colletotrichum sp. ON CHILLI FRUITS

EFFICACY OF Ageratum LEAF EXTRACT ON POSTHARVEST ROT CAUSED BY Aspergillus niger AND Colletotrichum sp. ON CHILLI FRUITS

Evaluation of In Vivo Toxicity of Dichloromethane: Methanolic Leaf Extracts of Prosopis juliflora in Female Wistar Albino Rats

Antifungal activity of Piper cubeba L. extract on spoilage fungi isolated from tomato, grapes and lemon

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