Studies on Substituted Beta Lactams Towards Ring Opening: Elimination Versus Rearrangement

Abstract

Beta lactams and products obtained from them through rearrangement reactions are extremely useful compounds of diverse interests. During the course of study of vinyl beta lactams and rearrangement of beta lactams, it has been observed that elimination reaction becomes much faster than rearrangement when substituted bromo beta lactam alcohol is exposed under nucleophilic reaction conditions.