1958
DOI: 10.1016/0006-3002(58)90515-8
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Studies on the electron transport system

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1959
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Cited by 89 publications
(14 citation statements)
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“…Yeast mitochondria as described in the preceding paper (24) are morphologically similar to those present in the cells of higher organisms, except for their smaller size (0.2 to 0.6 ~). The morphology of particles in the isolated fractions--initial sediment, Heavy III, and Light II--are shown, respectively, in Figs.…”
Section: Morphology Of the Isolated Particlessupporting
confidence: 52%
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“…Yeast mitochondria as described in the preceding paper (24) are morphologically similar to those present in the cells of higher organisms, except for their smaller size (0.2 to 0.6 ~). The morphology of particles in the isolated fractions--initial sediment, Heavy III, and Light II--are shown, respectively, in Figs.…”
Section: Morphology Of the Isolated Particlessupporting
confidence: 52%
“…The fixed material was washed in water, dehydrated, embedded in methacrylate, and sectioned as described in the preceding paper (24).…”
Section: Electron Microscopymentioning
confidence: 99%
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“…The mitochondrial membranes contain the different multienzyme complexes involved in these transformations; these complexes are arranged in highly ordered arrays (33,37,40,51). Although the first phase of the fine structural analysis of the mitoehondrion (53,54,67) established the base line for a correlation of structure and function (4,14,65,79,80), the shortcomings of the preparative techniques and of the resolution of the electron microscope limited the extent of meaningful correlation. With mitochondria, as with other lamellar systems (18,68,78), it is now apparent that the submicroscopic patterns of sectioned specimens fixed with osmium tetroxide reveal merely a general structural framework consisting essentially of lipoprotein.…”
Section: Introductionmentioning
confidence: 99%
“…The capacity for both electron transfer and oxidative phosphorylation was retained in an analogous particle (ETPI~). Electron microscopic studied-of these submitochondrial fractions by standard osmium fixation and thin sectioning techniques (14,33,79,80) indicated that the double-membraned structure was preserved in specimens of ETPm whereas only a single-membraned structure was observed in ETP. More extensive correlation of fine structure with function, however, could not be achieved in these early investigations.…”
Section: Introductionmentioning
confidence: 99%