Studies on the Toxicological Properties of Ethanol Stem-Bark Extract of Newbouldia laevis (P. Beauv) Seem in Rats
Abstract:This research aimed at evaluating the toxicological profile of ethanol stem-bark extract of N. laevis in Wistar rats. Repeated oral dose toxicity studies (28 and 90 days) were carried out with 32 rats for 28-day study and 40 rats for 90-day study. The rats were divided into 4 groups (A, B, C and D) of six rats per group and were treated with 250, 500 and 1,000 mg/kg body-weight of the extract for 28 and 90 days respectively. Blood samples were collected at the end of the experiment and were used for Biochemica… Show more
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