In today's world, high speed is an important factor to be considered in wireless communication systems. This is because high speed is required for access of video, images, and many others multimedia application. One way to achieve high data rate is OFDM. Orthogonal Frequency Division Multiplexing (OFDM) is a technique which transmitted data parallel and this data are orthogonal to each other, hence result high data rate in wireless transmission as large no. of data is transmitted at same time. Another way is MIMO system. To increase the diversity gain or to enhance the system capacity on time-variant and frequency-selective channels, OFDM may be combining with multiple transmitter antenna and receiver antenna, this resulting MIMO OFDM system. MIMO-OFDM, a new wireless 4G technologies, has capability of enhance data rate transmission and robustness against multi-path fading. In this paper, two techniques Least Square (LS) and Minimum Mean Square Error (MMSE) are used to analysis the performance of MIMO OFDM System also used to reduce BER.