Study Design of the Maycoba Project: Obesity and Diabetes in Mexican Pimas

Urquídez-Romero, René; Esparza-Romero, Julián; Chaudhari, Lisa S.; Begay, R. Cruz; Giraldo, Mauricio; Ravussin, Éric; Knowler, William C.; Hanson, Robert L.; Bennett, Peter H.; Schulz, Leslie O.; Valencia, Mauro E.

doi:10.5993/ajhb.38.3.6

Cited by 11 publications

(17 citation statements)

References 36 publications

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“…The study protocol, objectives, and benefits of the intervention program were explained. People who showed interest in participating were screened using anthropometry and clinical sociodemographic history questionnaires [ 27 ], and the FINDRISC (Finnish Diabetes Risk Score) questionnaire was used to identify subjects at a potential risk of T2D [ 28 ]. Subjects who met the following inclusion criteria were included: men and women between 20 and 65 years of age, overweight/obese (BMI ≥ 25 kg/m 2 ), at risk of T2D according to the FINDRISC questionnaire (score ≥ 12), being of Yaqui ethnicity, wanting to participate, and signing the informed consent form.…”

Section: Methodsmentioning

confidence: 99%

“…Body weight (kg) was obtained using a digital scale with a capacity of 200 kg ± 100 g (Seca 813), according to the established methodology [ 16 , 27 ].…”

Section: Methodsmentioning

confidence: 99%

“…Body mass index (BMI) was calculated by dividing weight in kilograms by the square of height in meters [ 16 , 27 ]. The height (m) was measured using a portable stadiometer (Seca 213) with an error range of 0.05 mm [ 16 , 27 ].…”

Section: Methodsmentioning

confidence: 99%

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Effectiveness of the Healthy Lifestyle Promotion Program for Yaquis with Obesity and Risk of Diabetes in the Short and Medium Term: A Translational Study

Castro-Juarez¹,

Serna-Gutiérrez

Dórame-López³

et al. 2020

Journal of Diabetes Research

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Type 2 diabetes (T2D) is a public health problem worldwide, and the main risk factor for its development is obesity. The Yaqui ethnic group of Sonora has serious obesity problems, resulting in an increased risk of T2D in its inhabitants. The objective of this study was to evaluate the effectiveness of a health promotion program on obesity parameters and cardiovascular risk factors in short- (6 months) and medium-term periods (12 months) in indigenous Yaquis of Sonora. The design is a translational clinical study of a single cohort with prepost intervention measurements in a sample of 93 subjects. The effectiveness of the program was evaluated by comparing obesity parameters, metabolic markers, and physical activity 6 and 12 months with those measured under basal conditions using a paired t -test or Wilcoxon rank-sum test. The short-term retention percentage was 58.0%. There was a decrease in body weight ( Δ = − 3.9 kg , p ≤ 0.05 ) and other obesity parameters, and an increase in physical activity and improvements in metabolic markers ( p ≤ 0.05 ) was observed. Similar findings were obtained for the medium-term period; body weight loss was also -3.9 kg ( p ≤ 0.05 ). The short and medium-term results of the program showed improvements in the obesity parameters and other cardiovascular risk factors of the participants. These results support the effectiveness of the program and its translation in this ethnic group.

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Section: Methodsmentioning

confidence: 99%

“…Body weight (kg) was obtained using a digital scale with a capacity of 200 kg ± 100 g (Seca 813), according to the established methodology [ 16 , 27 ].…”

Section: Methodsmentioning

confidence: 99%

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Effectiveness of the Healthy Lifestyle Promotion Program for Yaquis with Obesity and Risk of Diabetes in the Short and Medium Term: A Translational Study

Castro-Juarez¹,

Serna-Gutiérrez

Dórame-López³

et al. 2020

Journal of Diabetes Research

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“…Measurements made in the 1995 study were replicated as closely as possible, including a medical history, biochemical and anthropometric measures, physical activity and dietary assessments [17]. Early in the study, a repeat census was conducted to determine the current demographic profile of the study area.…”

Section: Environmental Changementioning

confidence: 99%

“…In spring, however, a series of dramatic paved switchbacks were constructed through the 1600-km-long spine of the Sierra Madre mountains. They have made Maycoba and the surrounding communities far more accessible [17]. …”

Section: Introductionmentioning

confidence: 99%

High-Risk Populations: The Pimas of Arizona and Mexico

Schulz

Chaudhari

2015

Curr Obes Rep

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The purpose of this review is first, to broadly summarize the long-term commitment that began in 1965 to studying type 2 diabetes and obesity through the cooperation of the Pima Indians of Arizona, and second, to discuss the investigations with the Pima Indians of Mexico that started in 1991. The later studies emphasize gene-environment interactions in the pathogenesis of these metabolic disorders. Through the participation of both groups of Pimas, the researchers made key findings with regard to the epidemiology, physiology, clinical assessment and genetics of type 2 diabetes and obesity.

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Changes in energy expenditure and physical activity over 15 years of environmental changes: The Maycoba project

Niclou,

Esparza‐Romero,

Urquidez‐Romero

et al. 2024

Obesity

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ObjectiveThis work aimed to parse out the role of changing environments on body composition, total energy expenditure, and physical activity in the Mexican Pima, a population experiencing rapid industrialization.MethodsUsing doubly labeled water, we compared energy expenditure and physical activity in a longitudinal cohort of Mexican Pima (n = 26; female: 12) in 1995 and 2010. Body mass and composition were assessed by bioimpedance analysis. To determine the effects of environmental factors on body weight independent of age, we compared the 1995 longitudinal cohort with an age‐ and sex‐matched cross‐sectional cohort (n = 26) in 2010.ResultsBody mass, fat mass, and fat‐free mass all significantly increased between 1995 and 2010. Despite a 13% average increase in body weight, weight‐adjusted total daily energy expenditure decreased significantly. Measured physical activity levels also decreased between 1995 and 2010, after we adjusted for weight.ConclusionsOur results suggest that the recent industrialization of the Maycoba region in Sonora, Mexico, has contributed to a decrease in physical activity, in turn contributing to weight gain and metabolic disease among the Mexican Pima.

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Study Design of the Maycoba Project: Obesity and Diabetes in Mexican Pimas

Cited by 11 publications

References 36 publications

Effectiveness of the Healthy Lifestyle Promotion Program for Yaquis with Obesity and Risk of Diabetes in the Short and Medium Term: A Translational Study

Effectiveness of the Healthy Lifestyle Promotion Program for Yaquis with Obesity and Risk of Diabetes in the Short and Medium Term: A Translational Study

High-Risk Populations: The Pimas of Arizona and Mexico

Changes in energy expenditure and physical activity over 15 years of environmental changes: The Maycoba project

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