Study of aerobic bacterial isolates and their antibiotic susceptibility pattern in chronic suppurative otitis media

Malkappa, Sateesh Kumar; Kondapaneni, Saileela; Surpam, Rajendra; Chakraverti, Trinain Kumar

doi:10.4103/0971-7749.103440

Cited by 29 publications

(20 citation statements)

References 6 publications

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“…Taneja Mansi et al and Taneja had reported S. aureus (33.3% and 30.71%, respectively) as the most common organism, which was most sensitive to clindamyci h, [12,13] while in a recent study, Malkappa et al have shown the incidence of S. aureus as 22.2% and Pseudomonas aeruginosa as 45.2%. [14] Klebsiella was the second most common microbe isolated in these cases with unsafe CSOM. Fairbanks [5] reported Staphylococcus as the second most common cause.…”

Section: Resultsmentioning

confidence: 98%

Bacterial flora of infected unsafe CSOM

et al. 2012

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Aim: Chronic suppurative otitis media (CSOM) is a common cause of hearing impairment, especially in rural population. This study was carried out to know about the bacterial fl ora and antibiotic sensitivity for better management of the disease and to reduce morbidity due to CSOM. Materials and Methods: This study was undertaken in a tertiary care center of western UP with an aim to study the bacterial fl ora and their sensitivity to a series of antibiotics in cases of CSOM (unsafe) with active purulent discharge. There was no history of topical or systemic antibiotic therapy in these patients in the last 3 months. Aural swabs were taken and cultured for aerobic bacteria. For cases showing growth on culture media, sensitivity for a series of antibiotics was studied to have an understanding of the antibiotics showing sensitivity and resistance. Results: A total of 62 (mean age 17.38 years) diagnosed cases of CSOM unsafe were included in the study. The study group included 38 males (61.29%) and 24 (38.71%) females. Fifty-four patients (87.09%) had unilateral diseases, while 8 patients (12.90%) had bilateral diseases. 94.28% of the ears showed growth on culture media. Majority of these ears showed monomicrobial growth (90.90%). Conclusion: The most common bacteria isolated in descending order were Pseudomonas, Klebsiella, Staphylococcus, Proteus, and Escherichia coli. Majority of the patients showed sensitivity to cefoperazone and salbactum (90.69%), ofl oxacin (79.06%), and ciprofl oxacin (79.06%). 95.35% of the patients showed resistance to amoxicillin.

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Section: Resultsmentioning

confidence: 98%

Bacterial flora of infected unsafe CSOM

et al. 2012

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“…8 Indiscriminate use of antibiotics has resulted in the emergence of multiple resistant strains of bacteria and the persistence of low-grade infections. 9,10 Among the bacteria, Pseudomonas aeruginosa (P. aeruginosa) has been particularly blamed for deep seated and progressive destruction of middle ear and mastoid structures through its toxins and enzymes. 11 The prevalence and susceptibility pattern of the organisms has been reported to vary with time and geographical area, probably due to indiscriminate use of the antibiotics.…”

Section: Introductionmentioning

confidence: 99%

Prevalence and antibiotic susceptibility of Pseudomonas aeruginosa isolated from chronic suppurative otitis media

Deshmukh¹,

Manthale²

2016

Int J Otorhinolaryngol Head Neck Surg

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2 INTRODUCTIONChronic suppurative otitis media (CSOM) is the most common middle ear infection characterized by recurrent ear discharges or otorrhoea through a tympanic perforation from the middle ear.1 In developed countries the incidence of CSOM has decrease but is higher in developing countries attributed to various factors like because of malnutrition, low socioeconomic society, poor personal hygiene, recurrent upper respiratory tract infection and lack of adequate primary health care facilities.2-4 Inadequate treatment of CSOM may lead to serious intra-cranial and extra-cranial complications like facial nerve paralysis, meningitis, mastoid abscess, deafness, lateral sinus thrombosis and intracranial abscess. 5Although the complication are less common now due to availability of broad spectrum antibiotics, the resistance of the causative organisms is very common. 6 The organisms isolated from CSOM include both aerobic (e.g. Pseudomonas aeruginosa) and anaerobic bacteria (e.g. ABSTRACTBackground: Chronic suppurative otitis media (CSOM) is the most common middle ear infection characterized by recurrent ear discharges or otorrhoea through a tympanic perforation from the middle ear. The organisms isolated from CSOM include both aerobic and anaerobic bacteria. Among the bacteria, Pseudomonas aeruginosa (P. aeruginosa) has been particularly blamed for deep seated and progressive destruction of middle ear and mastoid structures through its toxins and enzymes. The present study was done to determine the prevalence and antibiotic susceptibility of P. aeruginosa isolated from CSOM. Methods: This was a retrospective study conducted in a tertiary care hospital in South India in March 2016. Data was obtained from the microbiology records from January 2014 to January 2016. Patients who had active ear discharge for at least three months were included in the study. P. aeruginosa was identified by colony morphology, pigment production, characteristic musty or earthy odor. The identification was confirmed by motility and standard biochemical tests. Results: A total of 293 cases of CSOM were included in the study. Microbial growth was seen in 248 (84.6%) cases and remaining 45 cases did not show any growth. Among 248 bacterial growth, 87 (35%) were positive for P. aeruginosa. Most common organism was P. aeruginosa followed by Staphylococcus aureus. Highest resistance was seen with Gentamicin and Ofloxacin and least resistance with Imipenem. The increased resistance to Cephalosporin group is warning sign, as these are potent anti-Psuedomals. Conclusions: P. aeruginosa and Staphylococcus aureus were found to be the common cause of CSOM in the present study. P. aeruginosa was resistant to commonly used antimicrobials. There was no resistance seen with Imipenem and only two strains were resistant to Piperacillin+tazobactum. Regular evaluation of the microbiological pattern and antibiogram of isolates will help in decreasing the complications of CSOM.

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“…Various studies have shown similar pattern where ampicillin was found to be highly resistant. [21,22] Use of ampicillin as an empirical choice for treating cases of CSOM has to be reconsidered as the majority of the strains are resistant. In this era of multidrug resistance, resistance to ampicillin is of no surprise as this drug has been used as an empirical choice for many infections in outpatient departments.…”

Section: Section: Microbiologymentioning

confidence: 99%

A Study to Assist the Treatment in a Case of Chronic Suppurative Otitis Media by Doing Microbial Profile and Sensitivity Testing

Srinivasan¹,

Sophia²,

Jennifer³

2017

AIMDR

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Background: Chronic Suppurative otitis media (CSOM) is one of the commonest disease seen in all age groups. It is one of the leading causes of deafness if treatment is not initiated at early stage. As newer antibiotics are frequently used for the treatment of CSOM, change in the microbial flora is inevitable. The aim of this study is to know the organisms causing CSOM and the antibiotics that are effective against these microorganisms. Methods: This study was done in a 500 bedded tertiary care hospital and patients presenting with history of more than three months of ear discharge were included in the study. The ear discharge was taken with a sterile swab and sent to the microbiology laboratory for processing. Standard microbiological procedures were followed for identification and antibiotic sensitivity testing. Results: Our study showed staphylococcus aureus including methicillin resistant staphylococcus aureus (47%) as the predominant organism followed by pseudomonas sp (23%). Staphylococcus aureus was found to be highly sensitive to clindamycin (96%), gentamicin (85%) and ciprofloxacin (74%). Pseudomonas sp was found to be highly sensitive to imipenem, piperacillin-tazobactam and ciprofloxacin (90%).Conclusion: Staphylococcus aureus was the commonest organism causing CSOM in our study. Ampicillin was found to be highly resistant and ciprofloxacin was found to be an effective antibiotic to treat both gram positive and gram negative infections. Hence we conclude that ciprofloxacin can be used as an empirical antibiotic for patients with CSOM.

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Study of aerobic bacterial isolates and their antibiotic susceptibility pattern in chronic suppurative otitis media

Cited by 29 publications

References 6 publications

Bacterial flora of infected unsafe CSOM

Bacterial flora of infected unsafe CSOM

Prevalence and antibiotic susceptibility of Pseudomonas aeruginosa isolated from chronic suppurative otitis media

A Study to Assist the Treatment in a Case of Chronic Suppurative Otitis Media by Doing Microbial Profile and Sensitivity Testing

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