“Study of Hematological Profile in Malariaand Dengue Patients”

Abstract

Background: Malaria and dengue are the two most common vector borne diseases in India. They are transmitted to human by the bite of mosquito and causes different hematological manifestations. Aim: To investigate the alterations in hematological parameters in malaria and dengue patients and to differentiate hematological parameters in co-infection of dengue with malaria from infections of dengue and malaria alone. Material and method: This cross sectional observational study was done in 483 malaria and/or dengue patients whose blood samples were collected in the department of Pathology and department of Microbiology at Pt. J.N.M. Medical College and associated Dr. B.R.A.M. Hospital, Raipur. The study duration was 1 year from 1st January 2018 to 31st December 2018. Result: Out of 483 cases, 384 were dengue positive, 96 were malaria positive and 3 cases were co-infection. We observed that hematological parameters like WBC count, neutrophil %, RDW and PDW were significantly higher in malaria groups while lymphocyte %, monocyte %, RBC count, hemoglobin, hematocrit, MCH, MCHC, platelet count and plateletcrit were significantly higher in dengue group. Conclusion: This study concluded that all the patients presented with the febrile illness should be tested for both malaria and dengue. These two diseases presented with similar clinical manifestations that is why specific diagnostic testing along with complete blood count is necessary to confirm the diagnosis and to know the severity of the illness.