Study of hemostasis procedures for posterior epistaxis

Iimura, Jiro; Hatano, Atsushi; Ando, Yumiko; Arai, Chiaki; Arai, Satoshi; Shigeta, Yasushi; Kojima, Hiromi; Otori, Nobuyoshi; Wada, Kota

doi:10.1016/j.anl.2015.09.015

Cited by 33 publications

(39 citation statements)

References 11 publications

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“…In current studies, the fact that 56.6% of patients have a history of HT preoperatively and the diagnosis of HT has been made along with an epistaxis episode in 6.6% of them suggest that high blood pressure is a risk factor for posterior epistaxis. However, as seen in our study and in many other studies, the presence of hypertension in patients does not increase surgical failure in TESPAL (8,11).…”

Section: Discussionsupporting

confidence: 84%

“…If it can be seen, cauterizing the bleeding site primarily can reduce the possibility of re-bleeding in patients with epistaxis (11). If the bleeding site cannot be seen in the endoscopic examination, anterior nasal packing can be applied.…”

Section: Discussionmentioning

confidence: 99%

“…However, the application of anterior nasal packing without endoscopic examination may increase the bleeding, especially in patients with nasal septum deviation because it may damage the mucosa (12). TESPAL is recommended in bleedings that cannot be stopped despite anterior nasal packing or in patients with posterior epistaxis after the removal of the packing in 48-72 hours (11,13). On the other hand, the application of TESPAL without anterior nasal packing is another method in patients with posterior epistaxis (14).…”

Section: Discussionmentioning

confidence: 99%

“…It is not clear whether epistaxis is a result of HT or it is the reason for HT because it causes anxiety (17,18). The incidence of concomitant HT in patients undergoing TESPAL ranges from 30 to 60% (8,9,11,12). In current studies, the fact that 56.6% of patients have a history of HT preoperatively and the diagnosis of HT has been made along with an epistaxis episode in 6.6% of them suggest that high blood pressure is a risk factor for posterior epistaxis.…”

Section: Discussionmentioning

confidence: 99%

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Endoscopic Sphenopalatine Artery Ligation in Posterior Epistaxis: Retrospective Analysis of 30 Patients

İsmi¹,

Vayısoğlu²,

Özcan³

et al. 2016

Turk Arch Otorhinolaryngol

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Objective: Although posterior epistaxis is rarely seen, it is an important medical problem that both decreases the quality of life of the patient and causes difficulties in the management for otorhinolaryngologists. In this study, we aimed to present the results of 30 patients who underwent transnasal endoscopic sphenopalatine artery ligation (TESPAL) for posterior epistaxis in our department. Methods:The records of 30 patients who underwent TESPAL from January 2014 to April 2016 were analyzed retrospectively, and the relationship between perioperative factors and need for revision surgery was assessed. Results:The success rate of TESPAL in posterior epistaxis was 90%. There was no relationship between surgical failure and antiaggregant use (p=0.224), anticoagulant use (p=0.534), hypertension (p=0.564), previous nasal surgery (p=0.279), and bilateral TESPAL application (p=0.279). TESPAL was seen to be effective in cases with Osler-Weber-Rendu disease, pregnancy, and uncontrollable epistaxis after rhinoplasty surgery. Mortality was seen in one of our patients not related to endoscopic ligation in the follow-up period. Conclusion:TESPAL is an effective method in the treatment of posterior epistaxis. Hypertension, antiaggregant or anticoagulant use, bilateral sphenopalatine artery ligation, and previous nasal surgery do not seem to be factors leading to surgical failure.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Endoscopic Sphenopalatine Artery Ligation in Posterior Epistaxis: Retrospective Analysis of 30 Patients

İsmi¹,

Vayısoğlu²,

Özcan³

et al. 2016

Turk Arch Otorhinolaryngol

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“…Содержание малонового диальдегида (МДА) в суспензии эритроцитов определяли модифици-рованным для крови методом, описанным Р. А. Тимирбулатовым, Е. И. Селезневой [20] с исполь-зованием спектрофотометра при длине волны возбуждающего света 535 нм. Концентрацию МДА рассчитывали с использованием коэффициента молярной экстинкции 1,56 х 10 5 моль -1 см -1 .…”

Section: материалы и методыunclassified

Potential of Antioxidant Protection in Patients With Epistaxis

Владимировна¹,

Колмакова²,

Smirnova³

2017

Kuban. nauсh. med. vestnik

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ПОÒЕНЦИАЛ АНÒИОКСИДАНÒНОЙ ЗАЩИÒЫ У БОЛЬНЫХ С НОСОÂЫМИ КРОÂОÒЕЧЕНИЯМИ Федерации, пер. Нахичеванский, д 29, Ростов-на-Дону, Россия, 344022 АННОТАЦИЯТяжесть состояния больных при носовых кровотечениях(НК) зависит не только от объема кровопотери, но и от степени компенсации гипоксии, сопровождающей кровопотерю.Цель. Изучить антиоксидантные (АО) свойства сыворотки крови и интенсивность процессов перекисного окис-ления липидов (ПОЛ) в мембранах эритроцитов больных с НК различной степени тяжести.Материалы и методы. Исследовали 82 больных с носовыми кровотечениями различной степени тяжести. Ан-тиоксидантную активность сыворотки крови больных изучали методом хемилюминесценции, индуцированной ио-нами двухвалентного железа. Процессы перекисного окисления липидов изучали, оценивая активность ферментов антиоксидантной защиты -супероксиддисмутазы (СОД) и суммарную пероксидазную активность в эритроцитах крови, а также содержание в эритроцитах конечного продукта ПОЛ -малонового диальдегида (МДА).Результаты. Установлено, что что потенциал антиоксидантной защиты сыворотки и форменных элементов крови являются одним из важнейших звеньев патогенеза НК.Заключение. Высокая емкость антиоксидантной защиты может существенно снизить риск развития необрати-мых изменений в эритроцитах и развития клинических признаков глубокой тканевой гипоксии при НК. POTENTIAL OF ANTIOXIDANT PROTECTION IN PATIENTS WITH EPISTAXIS ABSTRACTThe status of patients with nose bleedings (NB) depends not only on the volume of blood loss, but also on the degree of compensation for hypoxia accompanying hemorrhage.Aim. The main aim of our research was to study the antioxidant properties of blood serum and the intensity of LPO processes in erythrocyte membranes of patients with epistaxis of varying severity.Materials and methods. 82 patients with nose bleeding of varying severity were examined. The antioxidant activity of the blood serum of patients was studied by the chemiluminescence method induced by divalent iron ions. The processes of lipid peroxidation were studied by evaluating the activity of antioxidant defense enzymes -superoxide dismutase (SOD) and total peroxidase activity in blood erythrocytes, as well as the content of the final product of LPO-malonic dialdehyde (MDA) in erythrocytes.Results. It has been established that the potential of antioxidantprotection of serum and formed elements of blood is one of the most important links in the pathogenesis of NB.Conclusion. High capacity of antioxidant protection can significantly reduce the risk of irreversible changes in erythrocytes and the development of clinical signs of deep tissue hypoxia in patients with epistaxis.

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