Study of Morphology and Hormone Receptor Status of Male Breast Lesions

Abstract

BACKGROUNDMale breast carcinoma is rare and therefore not detected on time. They also do not receive importance in studies. All male breast carcinomas received during the given period in Pathology Department at Government Medical College, Trivandrum were studied, graded, categorised, interpreted as per relevant standards and sub-typed according to their immunohistochemical profile. Appropriate statistical correlations have been applied. Hormonal study of these lesions helps to decide proper targeted chemotherapy for these cases and help in further treatment. In case of benign lesions like gynaecomastia, it can be useful in treating them with drug therapy so that patients can do away with unwanted surgeries and hassles. In view of the higher fatality rate, male breast cancers merit more serious study and early intervention.The objectives of this article are to study the clinico-pathological features of Male Breast Lesions and to assess the expression of Oestrogen Receptor and Progesterone Receptor in male breast lesions and also HER-2/neu in male breast carcinomas.