Study of plasma klotho and plasma copeptin level in adolescents with type 1 diabetes mellitus and relation to microvascular complications

Awad, Mohamed M; el-Shorbagy, E; Nasr, Ashraf Youssef; Hamed, Mohamed G.

doi:10.4103/ejode.ejode_13_19

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Copeptin As a Marker In Diabetes Mellitus1

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2022

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“…Awad et al [3] showed that there was a significant elevation of plasma copeptin levels in adolescents with T1DM, which is significantly higher in the presence of microvascular complications, principally diabetic kidney disease. Moreover, it was reported that there is a significant increase in serum copeptin levels accompanied by a positive correlation with the albumin/creatinine ratio in children with T1DM [14].…”

Section: Copeptin As a Marker In Diabetes Mellitusmentioning

confidence: 99%

Copeptin: A Novel Marker for Diagnosis and Prognosis of Various Diseases AssociatedWith Diabetes

Gomaa¹

2022

BIJGIM

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Copeptin is an arginine vasopressin (AVP) precursor whose C-terminal has evolved into 39 amino acids. This AVP precursor is converted into equimolar amounts of Copeptin, neurophysin II, and AVP. a strong connection between the release of AVP and copeptin was observed. Measurement of AVP concentration remains complicated since AVP is an unstable peptide and additionally it is bound by platelets. Copeptin remains stable in serum or plasma for several days in a warm environment. and testing for copeptin yields findings in one h. Consequently, the quantity of copeptin might serve as a perfect replacement for reflecting the level of AVP. Copeptin has become identified as a beneficial measure in various diseases. The physiology and structure of copeptin, as well as its potential, to act as a predictive and diagnostic indicator of different diseases associated with diabetes is the goal of the current review.

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Section: Copeptin As a Marker In Diabetes Mellitusmentioning

confidence: 99%

Copeptin: A Novel Marker for Diagnosis and Prognosis of Various Diseases AssociatedWith Diabetes

Gomaa¹

2022

BIJGIM

View full text Add to dashboard Cite

show abstract

Study of plasma klotho and plasma copeptin level in adolescents with type 1 diabetes mellitus and relation to microvascular complications

Cited by 1 publication

References 1 publication

Copeptin: A Novel Marker for Diagnosis and Prognosis of Various Diseases AssociatedWith Diabetes

Copeptin: A Novel Marker for Diagnosis and Prognosis of Various Diseases AssociatedWith Diabetes

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