Study of Relationship Between Depression and Quality of Life in Patients With Chronic Schizophrenia

Abstract

Depression is among the personality traits of schizophrenic patients, which results from psychotic features or is a consequence of a period of psychosis. Depression in schizophrenic patients is one of the important factors affecting their quality of life. The study population of this descriptive and analytic study consists of patients with chronic schizophrenia in Zahedan in 2014. The sample included 60 patients who simultaneously suffered from depression and were selected using random sampling (30 males and 30 females). The research instruments included the Schizophrenia Quality of Life Scale (SQLS) and the Beck Depression Inventory (the inventory was filled out by the tester). In order to form a statistics analysis, we used Pearson correlation and regression multivariate. Investigating the study hypotheses showed that there was a negative correlation between the high level of depression and low quality of life. the relationship between depression and the quality of life subscales showed that in women, the variable of symptoms and complications was a significant predictor; however, the other two variables (energy and motivation and psychosocial) were not significant predictors. In case of men, psychosocial variable was a significant predictor; however, the other two variables (energy and motivation and symptoms and complications) were not significant predictors. In general, depression on these patients makes discontent of life on them; therefore, elimination of their depression on their treatment is necessary.

HPA Axis in the Pathomechanism of Depression and Schizophrenia: New Therapeutic Strategies Based on Its Participation

“…In 2018 Dai et al [192], using the 17-item Hamilton Depression Rating Scale (HAMD-17), proved that depression occurred in about 54,6% of patients with schizophrenia. During another study [191] amid outpatients with diagnosed schizophrenia, only about 31% suffered from depression. These discrepancies may have been probably the result of different study settings or assessment instruments [193].…”

“…Generally, comorbid depression in schizophrenia often hasn't been properly diagnosed which doesn't allow the implementation of its treatment among patients [1,11]. Elucidating the correlation between schizophrenia and depression so as to be able to manage with it is indispensible [190,191]. Among many studies, we could see a discrepancy between the prevalence of comorbid depression in schizophrenia.…”

The prevalence and associated factors of depression among patients with schizophrenia in Addis Ababa, Ethiopia, cross-sectional study

“…According to the reports from several studies the presence of comorbid depression in patients with schizophrenia is associated with poor quality of life [11, 12], increased risk of suicide [13, 14], poor treatment adherence [15], frequent relapse and hospitalization [16], disability [17], poor physical health [18], worsening of psychosis [8], as well as poor treatment outcomes [17, 19] as compared to those schizophrenic patients without depression.…”

Effectiveness of gratitude disposition promotion program on depression and quality of life of chronic schizophrenic patients

“…In schizophrenic patients, about 80% of them experience depression and 20%–50% of them attempt to commit suicide in acute psychotic state or in chronic depressive state. [ 1 2 3 ]…”

“…Furthermore, depression, among the many factors affecting the quality of life of schizophrenic patients, has a great influence on the subjective quality of life. [ 3 4 5 6 7 ]…”