Study of the cytotoxic activity of di and triphenyltin(IV) carboxylate complexes

Anticancer activity of dinuclear gallium(III) carboxylate complexes

“…We have previously reported that carboxylic acids used as ligands in this study, showed no antiproliferative effect under physiological conditions on other human cancer cells [48]. The present study reveals that their corresponding gallium(III) complexes (1-5) showed a dose-dependent antiproliferative effect toward all cancer cell lines (Fig.…”

“…Following our research on the synthesis, characterization and cytotoxic properties of metal-based anticancer drugs [47][48][49][50][51], and encouraged by the good results observed for analogous tin(IV) complexes bearing the same carboxylato ligands [48], we present the synthesis, characterization and study of the cytotoxic activity of different dimeric gallium(III) carboxylate complexes.…”

Anticancer Applications and Recent Investigations of Metallodrugs Based on Gallium, Tin and Titanium

“…Notably, compound 14 presented from 30 to 112 times higher activity than that recorded for cisplatin. In this study, we observed that triphenyltin(IV) derivatives presented lower IC 50 values against all the studied cancer cell lines than their corresponding diphenyltin(IV) counterparts [34].…”

On the bioreactivity of triorganotin aminobenzoates. Investigation of trialkyl and triarylyltin(IV) esters of 3-amino and 4-aminobenzoic acids

“…Their activity is comparable with the tricyclohexyltin but inferior to the triphenyltin derivative 2-phenyl-1,2,3-triazole-4-carboxylates known already [30] as far as the HeLa is concerned while they are also comparative to the triphenyltin derivatives of 3-and 4-methoxylphenylacetate with respect to their HeLa but inferior with respect to the K562 cytotoxicity [46].…”