Study on calibrating the quadrupole mass spectrometers with gas mixture

Sun, W.; Wu, Chengyao; Cheng, Yongjun; Dong, Meng; Guo, Meiru; Li, Yali; Ren, Zhengyi; Jia, Wentao; Liu, Guoting; Wei, Ningfei

doi:10.1016/j.measurement.2020.108099

Cited by 12 publications

(13 citation statements)

References 22 publications

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“…In general, for the calibration of pure gases, the most intense signal (base peak) can be selected, but for complex mixtures, the base peaks overlap with the peaks (spectral interferences) of other gases. 11,18,20,22 For the choice of masses, we preferred to refer to the library provided by the MASsoft software (for Hiden analyzers) because the values can differ based on the machines. Karlegärd et al 15 and Le et al 11 report that the more fragments used in the calibration matrix, the more complex the method, the more accurate the analysis, but the longer the measurement time.…”

Section: Determination Of Interferences Using Databases Massoft and Nistmentioning

confidence: 99%

“…24,27 The QMS has low long-term stability; 22,23,28 therefore, its use requires a regular and accurate setup calibration phase. Another difficulty related to the use of the MS is the choice of characteristic peaks (m/z) 11,15,22,27 with as few interferences as possible. For a mixture composed of several gas species, the molecules are ionized and fragmented; these fragments are then separated based on their mass-to-charge ratio (m/z).…”

mentioning

confidence: 99%

“…Several QMS calibration methods for online gas composition measurement were proposed by many studies in various fields over the past decades. 4,5,11,[15][16][17][18][19][20][21][22][23][24][25][26] Nevertheless, online analysis of complex mixtures consisting of several gases (noble gases, N 2 , CO 2 , CO, O 2 , H 2 S, hydrocarbons, etc.) at lower concentrations is still challenging.…”

mentioning

confidence: 99%

“…The parameters of the mass spectrometer that allow the quality and accuracy of the calibration to be assessed (sensitivity, linearity, stability, and repeatability) are difficult to control. 24,27 The QMS has low long-term stability; 22,23,28 therefore, its use requires a regular and accurate setup calibration phase. Another difficulty related to the use of the MS is the choice of characteristic peaks (m/z) 11,15,22,27 with as few interferences as possible.…”

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confidence: 99%

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Development of quantitative detection method for mass spectrometry coupled to an infrared laser spectroscope (Picarro) to monitor in nitrogen matrix a complex gas mixture of H₂, He, CO, N₂, Ne, O₂, Ar, CO₂, H₂S, CH₄, C₂H₄, C₂H₆, C₃H₆, C₃H₈, i‐C₄H₁₀, n‐C₄H₁₀, and C₅H₁₂

Keita¹,

Noirez

Berthe

et al. 2023

Rapid Comm Mass Spectrometry

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RationaleThe deep geological repository is considered the international reference for radioactive waste management. All gas exchanges must be understood in the context of the feasibility of such a repository. The technological challenge is to continuously monitor a wide range of gaseous molecules at low concentrations in confined spaces.MethodsA gas monitoring station, composed of two complementary analyzers, was developed: an electron impact quadrupole mass spectrometer (HPR‐20 R&D Hiden Analytical) and an infrared laser spectroscope (Picarro). The spectrometer was calibrated using simple mixtures (i.e., C2H6 in N2) and multiple mixtures (i.e., H2, He, CO2, CH4, and O2 in N2) at different concentrations to correct interferences. A matrix calculation is proposed to calculate the relative concentrations.ResultsThe method developed allows the measurement of gaseous species: light hydrocarbons, noble gases, sulfides, greenhouse gases, oxygen, hydrogen, and nitrogen in the same mixture. For each gas, the SDs and the limits of detection and quantification were calculated. The method was validated by comparing the concentrations of the measured gas species with the reference values of two standard gas cylinders.ConclusionsCalibration of a complex gas mixture remains a challenge because fragmentation of molecules, especially hydrocarbons, reduces the sensitivity of the method. The method developed is suitable for continuous gas monitoring in a confined environment and can be implemented to perform experiments in underground structures: galleries, microtunnels (cells), and boreholes.

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Section: Determination Of Interferences Using Databases Massoft and Nistmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Development of quantitative detection method for mass spectrometry coupled to an infrared laser spectroscope (Picarro) to monitor in nitrogen matrix a complex gas mixture of H₂, He, CO, N₂, Ne, O₂, Ar, CO₂, H₂S, CH₄, C₂H₄, C₂H₆, C₃H₆, C₃H₈, i‐C₄H₁₀, n‐C₄H₁₀, and C₅H₁₂

Keita¹,

Noirez

Berthe

et al. 2023

Rapid Comm Mass Spectrometry

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“…factors and transmitting e ciencies of a quadrupole mass lter (cf.,Summers, 1969;Lieszkovsky et al, 1990;Jousten, 2008;Malyshev and Middleman, 2008;Yoshida and Arai, 2018; Operating manual of Transpector MPH gas analysis system, PN 074-555-P1C, In con). The relative sensitivities reported for QMS in previous studies indicate more or less variation, but those are within 1 ±~50 % for the above species in most cases (e.g.,Mahaffy et al, 2011;Hirashita et al, 2013;Yoshida et al, 2014;Sun et al, …”

mentioning

confidence: 99%

The GAs Extraction and Analyses system (GAEA) for immediate extraction and measurements of volatiles in the Hayabusa2 sample container

Miura

Okazaki

Takano

et al. 2022

Preprint

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Hayabusa2 returned surface samples from the C-type near-Earth asteroid (162173) Ryugu to Woomera, South Australia, in December 2020. The samples returned from Ryugu are expected to contain volatile components reflecting its primitive nature and solar wind components due to exposure to space. Such volatiles may partly be released inside the sealed sample container enclosing Ryugu samples due to particle destruction or container heating in a contingency case. In order to collect and analyze volatiles released in the container prior to the container opening, we set up a gas extraction and analyses system (GAEA: GAs Extraction and Analyses system). The system requires ultra-high vacuum condition, small vacuum line volume to minimize dead volume and simple configuration as well as having an interface to connect the container. The system includes gas bottles for passive collection of volatiles at room temperature and bottles for active collection at liquid nitrogen temperature. A quadrupole mass spectrometer is installed to analyze gases in the vacuum line, and a non-evaporative getter pump is also used when noble gases are analyzed. The rehearsal operation of GAEA was made at ISAS/JAXA as well as transportation tests in Japan. In November 2020, it was transported safely to the Quick Look Facility (QLF) in Woomera. It was set up at the QLF and worked well as planned for collection and analysis of gas components from the returned sample container. Here we report the concept, design and calibration results for the GAEA and an outline of analytical protocols applied in Woomera.

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Addressing challenges with evaluating hydrogen‐selective membrane performance by quadrupole mass spectrometry

Kurtishaj,

Žumer,

Nemanič

et al. 2024

J Mass Spectrom

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Hydrogen separation using nanostructured membranes has gained research attention because of its potential to produce high‐purity hydrogen by separating gases at the molecular level. Quadrupole mass spectrometry (QMS) is one method to evaluate these membranes' effectiveness in separating hydrogen from gas mixtures. However, quantifying gases in a mixture with QMS is challenging, especially when heavier gas ions interfere with a light gas ion, resulting in lower quantification accuracy. This study addresses this challenge by presenting a detailed calibration procedure that significantly improves hydrogen quantification accuracy up to a factor of 2.5. CO and CO2 were chosen as interfering gases because they are commonly released in conventional hydrogen production processes. By carefully evaluating the performance of these membranes, new opportunities for hydrogen separation may be realized.

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Study on calibrating the quadrupole mass spectrometers with gas mixture

Cited by 12 publications

References 22 publications

The GAs Extraction and Analyses system (GAEA) for immediate extraction and measurements of volatiles in the Hayabusa2 sample container

Addressing challenges with evaluating hydrogen‐selective membrane performance by quadrupole mass spectrometry

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Study on calibrating the quadrupole mass spectrometers with gas mixture

Cited by 12 publications

References 22 publications

Development of quantitative detection method for mass spectrometry coupled to an infrared laser spectroscope (Picarro) to monitor in nitrogen matrix a complex gas mixture of H2, He, CO, N2, Ne, O2, Ar, CO2, H2S, CH4, C2H4, C2H6, C3H6, C3H8, i‐C4H10, n‐C4H10, and C5H12

Development of quantitative detection method for mass spectrometry coupled to an infrared laser spectroscope (Picarro) to monitor in nitrogen matrix a complex gas mixture of H2, He, CO, N2, Ne, O2, Ar, CO2, H2S, CH4, C2H4, C2H6, C3H6, C3H8, i‐C4H10, n‐C4H10, and C5H12

The GAs Extraction and Analyses system (GAEA) for immediate extraction and measurements of volatiles in the Hayabusa2 sample container

Addressing challenges with evaluating hydrogen‐selective membrane performance by quadrupole mass spectrometry

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