Study on Chagas disease occurrence in the municipality of Monte Negro, State of Rondônia, Brazilian Amazon

Carvalho, Elaine Oliveira Costa de; Rosa, João Aristeu da; Carvalho, Anderson Antonio de; Chaves, Hialli Cristine Oliveira; Souza, Everton Almeida de; Ostermayer, Alejandro Luquetti; Camargo, Luís Marcelo Aranha

doi:10.1590/s0037-86822011000600010

Cited by 9 publications

(2 citation statements)

References 20 publications

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“…Of 4895 articles identified, 42 were considered eligible for the review (Aras et al, 2002;Arruda et al, 1984;Bento et al, 1984;Bento et al, 1989;Bento et al, 1992;Bezerra et al, 1983;Boia et al, 1999;Borges-Pereira et al, 2001;Borges-Pereira et al, 2006;Borges-Pereira et al, 2008;Brito et al, 2012;Carvalho et al, 2011a;Carvalho et al, 2003;Carvalho et al, 2011b;Coimbra et al, 1992;Corrêa et al, 2011;Coura et al, 1995a;Coura et al, 1995b;Coura et al, 2002;Dantas-Maia et al, 2007;Dias et al, 2002a;Diotaiuti et al, 2000;Escolano et al, 1989;Figueredo-Silva et al, 1991;Fonsêca et al, 2012;Gazin et al, 2004;Lima et al, 2012;Luitgards-Moura et al, 2005;Machado et al, 1998;Magalhães et al, 2011;Massaro et al, 2008;Montoya et al, 2003;Passos et al, 1997; Peñaranda-Carrillo et Pereira and Coura, 1986;Pereira and Coura, 1987;Silva et al, 2009;Silva et al, 2010;Silva and Goldenberg, 2008;Tachibana et al, 1999;Valente et al, 1998) (Fig.…”

Section: Literature Search Resultsmentioning

confidence: 99%

Prevalence of Chagas disease in Brazil: A systematic review and meta-analysis

et al. 2014

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Chagas disease is a major public health problem in Brazil and Latin America. During the last years, it has become an emerging problem in North America and Europe due to increasing international migration. Here we describe the prevalence of Chagas disease in Brazil through a systematic review. We searched national and international electronic databases, grey literature and reference lists of selected articles for population-based studies on Chagas disease prevalence in Brazil, performed from 1980 until September 2012. Forty-two articles with relevant prevalence data were identified from a total of 4985 references. Prevalence ranged from 0% to 25.1%. Most surveys were performed in the Northeast region, especially in the state of Piauí. We observed a high degree of heterogeneity in most pooled estimates (I(2)>75%; p<0.001). The pooled estimate of Chagas disease prevalence across studies for the entire period was 4.2% (95% CI: 3.1-5.7), ranging from 4.4% (95% CI: 2.3-8.3) in the 1980s to 2.4% (95% CI: 1.5-3.8) after 2000. Females (4.2%; 95% CI: 2.6-6.8), >60 year-olds (17.7%; 95% CI: 11.4-26.5), Northeast (5.0%; 95% CI: 3.1-8.1) and Southeast (5.0%; CI: 2.4-9.9) regions and mixed (urban/rural) areas (6.4%; 95% CI: 4.2-9.4) had the highest pooled prevalence. About 4.6 million (95% CI: 2.9-7.2 million) of people are estimated to be infected with Trypanosoma cruzi. The small number of studies and small-scale samples of the general population in some areas limit interpretation, and findings of this review do not necessarily reflect the situation of the entire country. Systematic population-based studies at regional and national level are recommended to provide more accurate estimates and better define the epidemiology and risk areas of Chagas disease in Brazil.

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Section: Literature Search Resultsmentioning

confidence: 99%

Prevalence of Chagas disease in Brazil: A systematic review and meta-analysis

et al. 2014

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“…Carvalho et al 27 observed a low invasion of triatomine in homes and a pattern of rural properties in Monte Negro, Rondônia, which do not favor the domiciliation of triatomine. In this municipality, the houses are mostly made of concrete and roofs are made of tiles, including henhouses and other deposits; in the same study, a large amount of triatomine were found in Orbygnia speciosa (Babaçu) palm trees, which mostly grow in pasture areas.…”

Section: Discussionmentioning

confidence: 97%

Chagas Disease in the Western Brazilian Amazon: Epidemiological Overview from 2007 to 2018

Madeira

Jesus

Moraes

et al. 2021

jhgd

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Introduction: Chagas disease (CD) is a disease caused by the protozoan flagellates of the Kinetoplastid order Trypanosoma cruzi. Approximately 8,000,000 people are infected worldwide, mainly in Latin America, causing disabilities and more than 10,000 deaths per year. Objective: This study aimed to describe the epidemiological panorama of CD in the Western Brazilian Amazon from 2007 to 2018. Methods: In this ecological study, secondary data regarding the confirmed cases of T. cruzi infection in the states of Acre, Amazonas, Rondônia, and Roraima were collected from the Single Health System Notification Information System of the Department of Informatics of the Single Health System and were analyzed. The data were used to characterize the epidemiological profile of T. cruzi infection and to determine the frequency of infection in Western Amazonia. Results: A total of 184 cases of CD were reported in Western Amazonia, and the highest number of cases was reported in the states of Amazonas and Acre. Conclusion: The epidemiological panorama of the Western Brazilian Amazon from 2007 to 2018 includes a greater number of cases of T. cruzi infection in men aged 20–39 years and those living in rural areas. Oral transmission was prevalent in the region during the study, and the highest number of cases was reported in the months of April and December. Epidemiological data are an important resource for understanding the dynamics of CD and the main aspects related to the health-disease process.

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The Burden of Chagas Disease: Estimates and Challenges

2015

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Chagas disease, caused by infection with the protozoa Trypanosoma cruzi is transmitted most often by Triatominae insect vectors, but also through blood transfusion, organ transplant, and congenital transmission. Between 5 and 18 million people are currently infected and the infection is estimated to cause more than 10,000 deaths annually. The disease has 3 phases: acute, indeterminate, and chronic. The acute phase immediately follows infection. It is typically asymptomatic but produces fever and malaise in up to 5% of people. The indeterminate phase is asymptomatic. More than one-half of those infected will remain in this phase for life and never experience long-term sequelae. After a decade or more, 20% to 30% of people will experience chronic cardiovascular Chagas disease with sequelae including heart failure, arrhythmias, and thromboembolism. Another 15% to 20% will experience chronic digestive sequela including megaesophagus and megacolon. A complete accounting of the burden of Chagas disease requires estimating the prevalence of the infection, the prevalence of each of its sequelae among those with the infection, and the number of deaths attributable to the infection. Attempts to estimate Chagas disease prevalence are complicated by several challenges imposed by the disease's extreme spatial heterogeneity, quickly evolving temporal trends, the decades-long lag between infection and symptomatic disease, biased prevalence data, incomplete recognition of Chagas-attributable deaths, limited data on sequela, and a near total absence of data outside of endemic countries. Even though researchers have found methodological approaches to dealing with these challenges, there is a need for better data.

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Study on Chagas disease occurrence in the municipality of Monte Negro, State of Rondônia, Brazilian Amazon

Cited by 9 publications

References 20 publications

Prevalence of Chagas disease in Brazil: A systematic review and meta-analysis

Prevalence of Chagas disease in Brazil: A systematic review and meta-analysis

Chagas Disease in the Western Brazilian Amazon: Epidemiological Overview from 2007 to 2018

The Burden of Chagas Disease: Estimates and Challenges

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