Study on Evaluation of Serum Gamma-Glutamyl Transferase (Ggt) Levels in Acute Coronary Syndrome

Dhanju, Avtar Singh; Singla, Deepshikha; Singh, Phool; Chhabra, Ajay; Kaur, Sukhraj

doi:10.36106/ijar/4109004

Cited by 1 publication

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…19 We found that GGT has a significant positive correlation with triglyceride levels, similar to results reported by akpek et al and Jimba et al 16,20 This study's Findings emphasize that Serum GGT levels correlated positively according to (Spearman's rho) with VLDL-C, in agreement with the results of Dhanju and co-authors, who showed that there is a statistically significant positive relationship in GGT with VLDL-C among CAD patients. 21 The available data have shown a significant positive relationship between GGT and CRP, these results are also supported by Akpek and his colleagues. 16 Another study by Emiroglu supported our results, who performed a comparative analysis of serum GGT and…”

Section: Characteristicssupporting

confidence: 64%

Evaluation of serum gamma-glutamyl transferase among patients with coronary artery disease in Erbil city

Neemat,

Y. Muhammad Amin

2023

Zanco J Med Sci

View full text Add to dashboard Cite

Background and objective: The leading cause of morbidity and mortality globally is coronary artery disease (CAD). One of the recent new parameters for evaluating CAD is Serum GGT, which has been shown to be a predictor of coronary artery status irrespective of the traditional cardiovascular risk variables. This study aimed to evaluate and assess the correlation between serum GGT and other variables among patients with CAD in comparison with healthy subjects. Methods: A case-control prospective study. Subjects were grouped into Group I (CAD patients-117 individuals) and Group II (healthy Subjects-83 individuals) based on their Coronary Angiographic profile at surgical specialty Hospital-Cardiac Center-Erbil/Iraq. Parameters of S. GGT, S. total cholesterol, S.HDL-C, S.LDL-C, S. VLDL-C, and S.TG, S. (25)OH vitamin D, serum troponin T, S.CK-MB, and CRP were assessed for both groups. Results: The study population included 58% of male and 42% of female participants, with an age range of 30-77, with a mean of 56.13± 10.5 years old. The Pearson’s correlation coefficient of serum GGT with other variables showed that the relation between serum GGT with VLDL-C, CRP, and Triglyceride among CAD patients was found to be a weakly positive correlation and statistically significant (r=0.3, P = 0.004), (r=0.2, P = 0.031), and (r=0.3, P = 0.007) respectively. Conclusion: The present study showed that S.GGT as a new potential biochemical marker for preclinical atherosclerosis, would be a useful and important marker for assessing and evaluating risk factors of coronary artery disease and to further evaluations for CAD.

show abstract