Study on skin infection model of Staphylococcus aureus based on analytic hierarchy process and Delphi method

Liang, Jiaxin; Zou, Guofa; Li, Zhuoshi; Tao, Shu-Hong; Guo, Libing; Tang, Chunping; Jin-hong, Zhang; Deng, Zixin; Chen, Yanfen

doi:10.1016/j.heliyon.2023.e16327

Cited by 6 publications

(2 citation statements)

References 36 publications

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“…This is supported by Roblin et al (2023) who highlights the revenue losses due to cryptosporidiosis among farmers [97]. While issues persist and sustainability is questioned in the small-scale dairy sector, many researchers [22,[98][99][100][101][102][103][104] devised innovative approaches to track and mitigate livestock sickness occurrence in the dairy farming enterprises, and SSDFs in the region need to be concerted about the available tools which they can use to track and safeguard their livestock from diseases.…”

Section: Discussionmentioning

confidence: 99%

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Sustainability of Rural Small-Scale Farmers Using a Thematic Content-Fed Analytic Hierarchy Process

et al. 2023

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Small-scale dairy farming plays a pivotal role in the development of rural economies and has become a key source for job creation and poverty alleviation. However, the survival rate of these enterprises is compromised due to multifaceted challenges. As a result, the newly established or emerging small scale dairy businesses are not sustainable. The objective of this paper is to therefore investigate the determinants affecting sustainability of small-scale dairy enterprises and to develop a framework for failure minimization. The study used purposive snowball sampling techniques to invite small-scale dairy farmers (SSDFs) in Bojanala Platinum District, North West Province, South Africa. The data were analyzed using thematic content analysis (TCA) for factor derivation and ranked using the analytic hierarchy process (AHP). The study revealed the high cost of agricultural inputs, medication and electricity, followed by a lack of agricultural services, and unpredictable weather patterns due to climate change, which were regarded as priority factors proliferating high failure levels and unsustainability by the local farmers. Meanwhile, loadshedding and cattle theft were regarded as low priority factors affecting farming sustainability. The high level of failure in this industry diminishes the chances of farmers to obtain funding or credit; poorer farmers end up falling back into poverty as a consequence of market circumstances beyond their control. The paper concludes that small-scale dairy farming should be revised as part of a broader livelihood strategy by all stakeholders, while continuously pursuing alternative access points to achieve prosperous rural livelihoods, local market information and access, and risk optimization. With the prospects of future climate, geopolitical and environmental crisis, considering how local small-scale dairy farmers (SSDFs) react and use information technology is vital to their sustainability and providing policy relevant knowledge. Furthermore, the SSDFs should be exposed to agricultural funders in their localities, and also access to agricultural sector training authority (AGRISETA) services should be made available for local farmers to receive training for proposal writing to apply for funds.

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Section: Discussionmentioning

confidence: 99%

“…Roblin et al (2023) highlighted the revenue losses due to cryptosporidiosis among farmers [97]. Other researchers [22,[98][99][100][101][102][103][104] devised innovative approaches to track and mitigate livestock sickness occurrence in the dairy farming enterprises.…”

Section: Theoretical Frameworkmentioning

confidence: 99%

Sustainability of Rural Small-Scale Farmers Using a Thematic Content-Fed Analytic Hierarchy Process

et al. 2023

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The ever‐changing microenvironment of Staphylococcus aureus in cutaneous infections

Zhou,

Tian,

et al. 2024

Anim Models and Exp Med

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BackgroundStaphylococcus aureus is responsible for the majority of skin and soft tissue infections, which are often diagnosed at a late stage, thereby impacting treatment efficacy. Our study was designed to reveal the physiological changes at different stages of infection by S. aureus through the combined analysis of variations in the skin microenvironment, providing insights for the diagnosis and treatment of S. aureus infections.MethodsWe established a murine model of skin and soft tissue infection with S. aureus as the infectious agent to investigate the differences in the microenvironment at different stages of infection. By combining analysis of the host immune status and histological observations, we elucidate the progression of S. aureus infection in mice.ResultsThe results indicate that the infection process in mice can be divided into at least two stages: early infection (1–3 days post‐infection) and late infection (5–7 days post‐infection). During the early stage of infection, notable symptoms such as erythema and abundant exudate at the infection site were observed. Histological examination revealed infiltration of numerous neutrophils and bacterial clusters, accompanied by elevated levels of cytokines (IL‐6, IL‐10). There was a decrease in microbial alpha diversity within the microenvironment (Shannon, Faith's PD, Chao1, Observed species, Simpson, Pielou's E). In contrast, during the late stage of infection, a reduction or even absence of exudate was observed at the infected site, accompanied by the formation of scabs. Additionally, there was evidence of fibroblast proliferation and neovascularization. The levels of cytokines and microbial composition gradually returned to a healthy state.ConclusionThis study reveals synchrony between microbial composition and histological/immunological changes during S. aureus‐induced SSTIs.

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Various crystalline forms of realgar exhibit differentiated anti-abscess and anticancer effects based on a PXRD analysis and biological evaluation

Wang,

Zhang,

Shan

et al. 2025

Journal of Ethnopharmacology

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Study on skin infection model of Staphylococcus aureus based on analytic hierarchy process and Delphi method

Cited by 6 publications

References 36 publications

Sustainability of Rural Small-Scale Farmers Using a Thematic Content-Fed Analytic Hierarchy Process

Sustainability of Rural Small-Scale Farmers Using a Thematic Content-Fed Analytic Hierarchy Process

The ever‐changing microenvironment of Staphylococcus aureus in cutaneous infections

Various crystalline forms of realgar exhibit differentiated anti-abscess and anticancer effects based on a PXRD analysis and biological evaluation

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