Study on the effect of steady, simple pulsatile and physiological pulsatile flows through a stenosed artery

Goswami, P.; Mandal, Dipak Kumar; Manna, Nirmal K.; Chakrabarti, Somnath

doi:10.1007/s00231-014-1334-0

Cited by 9 publications

(4 citation statements)

References 34 publications

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“…The numerical results obtained from the simulation using the in-house CFD code are compared with the numerical and experimental results of Womersley [21] and Ojha et al [22] respectively. The differences between the predictions and experimental data are found to be a good agreement, which is shown by our previous published work, Goswami et al [23]. Timeaveraged wall pressure, fractional flow separation, peak time-averaged wall shear stress, low time-averaged wall shear stress, oscillatory shear index and endothelial cell activation potential have been taken into consideration for the analyzing of fluid mechanical features of realistic pulsatile flow through the stenosed arteries with mild stenosis (PR 30%), moderate stenosis (PR 50%) and severe stenosis (PR 70%).…”

Section: Resultssupporting

confidence: 88%

Numerical investigations of various aspects of plaque deposition through constricted artery

Goswami

Mandal

Manna

et al. 2019

JMES

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The pulsatile blood flow through constricted artery generates fluid mechanical forces on internal layer of artery, endothelium. These fluid mechanical factors affect endothelial lining from keeping artery healthy. In this paper, a series of numerical simulations of modeled bell shaped stenosed artery have been carried out for investigation of fluid mechanical factors of realistic pulsatile flow at the inlet of modeled stenosis with bell shaped geometry. The governing equations for two-dimensional unsteady laminar flow of incompressible fluid are solved by finite volume method followed by SIMPLER algorithm. The fluid mechanical factors, particularly wall pressure, streamline contour, peak wall shear stress, low wall shear stress and oscillatory shear index, having inferences to the arterial disease, are investigated by simulation results of different percentage of restrictions. All these parameters have a noticeable impact for the plaque deposition. The impacts of Reynolds number and Womersley number for both of mild stenosis and severe stenosis on arterial disease, atherosclerosis are also investigated by evaluating fractional flow reverse and oscillatory shear potential.

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Section: Resultssupporting

confidence: 88%

Numerical investigations of various aspects of plaque deposition through constricted artery

Goswami

Mandal

Manna

et al. 2019

JMES

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“…The numerical results obtained from the simulation using the in-house CFD code [Goswami, Mandal, Manna and Chakrabarty, 2014 ] Blood flow velocity changes in the restriction zone and wall shear changes drastically as well. Therefore, it is very imperative to observe the distribution pattern of wall shear stress in the stenotic zone.…”

Section: Resultsmentioning

confidence: 99%

Analysis of Wall Shear Parameters of Physiological Pulsatile Flow Through Mild and Severe Arterial Stenosis and Correlation to Atherosclerosis

Goswami

Mandal²,

Manna

et al. 2017

Mijst

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“…Buchanan et al (2000) reported that even though the value of Wo has a major influence on the flow field, haemodynamic parameters are primarily controlled by the Reynolds number (Re). Goswami et al (2014) reported the effect of inlet waveforms on disease progression with the help of wall haemodynamic parameters such as WSS and oscillatory shear index (OSI). Choosing a suitable rheological model for blood has several implications.…”

Section: Introductionmentioning

confidence: 99%

Numerical simulation of pulsatile blood flow through eccentric double stenosed carotid artery

Rajmane,

Tiwari

2023

HFF

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Purpose This study aims to perform three-dimensional numerical computations for blood flow through a double stenosed carotid artery. Pulsatile flow with Womersley number (Wo) of 4.65 and Reynolds number (Re) of 425, based on the diameter of normal artery and average velocity of inlet pulse, was considered. Design/methodology/approach Finite volume method based ANSYS Fluent 20.1 was used for solving the governing equations of three-dimensional, laminar, incompressible and non-Newtonian blood flow. A high-quality grid with sufficient refinement was generated using ICEM CFD 20.1. The time-averaged flow field was captured to investigate the effect of severity and eccentricity on the lumen flow characteristics. Findings The results show that an increase in interspacing between blockages brings shear layer instability within the region between two blockages. The velocity profile and wall shear stress distribution are found to be majorly influenced by eccentricity. On the other hand, their peak magnitude is found to be primarily influenced by severity. Results have also demonstrated that the presence of eccentricity in stenosis would assist in flow development. Originality/value Variation in severity and interspacing was considered with a provision of eccentricity equal to 10% of diameter. Eccentricity refers to the offset between the centreline of stenosis and the centreline of normal artery. For the two blockages, severity values of 40% and 60% based on diameter reduction were permuted, giving rise to four combinations. For each combination, three values of interspacing in the multiples of normal artery diameter (D), viz. 4D, 6D and 8D were considered.

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Study on the effect of steady, simple pulsatile and physiological pulsatile flows through a stenosed artery

Cited by 9 publications

References 34 publications

Numerical investigations of various aspects of plaque deposition through constricted artery

Numerical investigations of various aspects of plaque deposition through constricted artery

Analysis of Wall Shear Parameters of Physiological Pulsatile Flow Through Mild and Severe Arterial Stenosis and Correlation to Atherosclerosis

Numerical simulation of pulsatile blood flow through eccentric double stenosed carotid artery

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