Study on the Formation and Properties of Liquid Crystal Emulsion in Cosmetic

Zhang, Wanping; Liu, Lingyan

doi:10.4236/jcdsa.2013.32022

Cited by 24 publications

(22 citation statements)

References 9 publications

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“…In the present study, the addition of fennel oil show no significant effect on cream structure, all of our formulations displayed a pseudoelastic behavior also known as shear thinning behavior, as the viscosity declined with increasing of shear stress. This behavior is ty pical of many commercial systems since it improves spreading and penetrability of the product on the skin after topical preparations (Zhang and Liu, 2013) (Fig. 2b).…”

Section: Rheological Properties Of Moisturizing Creams Enriched With mentioning

confidence: 87%

Fennel oil and by-products seed characterization and their potential applications

Ahmad

Talou

Saad

et al. 2018

Industrial Crops and Products

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Section: Rheological Properties Of Moisturizing Creams Enriched With mentioning

confidence: 87%

Fennel oil and by-products seed characterization and their potential applications

Ahmad

Talou

Saad

et al. 2018

Industrial Crops and Products

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“…This network is gradually broken with increasing shear rate, resulting in a reduction of the internal resistance of the system, and ultimately decreasing the viscosity. This rheological parameter indicates that sample H1 can show good spreadability during application in the skin (Alam, Aramaki, 2009;Ribeiro, Morais, Eccleston, 2004;Zhang, Liu, 2013;Isaac et al, 2012). It can be correlated with the spreadability and with how easy formulation flow from package (Niraula et al, 2004).…”

Section: Determination Of Rheological Behaviormentioning

confidence: 98%

Organic cocoa extract -loaded surfactant-based systems intended to skin bioadhesion

Fonseca-Santos

Funagoshi

Oliveira

et al. 2017

Braz. J. Pharm. Sci.

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This study was to develop, characterize, and evaluate the physical-chemical stability, in vitro antioxidant activity and in vitro safety profile of liquid crystalline systems (LCS) and microemulsions (MEs) with and without organic cocoa (OC) extract. LCS stabilized by surfactant polyoxyethylene 20 cetyl ether, containing water and oleic acid were studied. LCS and MEs were characterized using polarized light microscopy, small angle X-ray scattering, rheology and in vitro bioadhesion, and were evaluated for a period of 30 days by visual aspects, centrifuge test, pH value and relative density. PLM and SAXS assays showed the presence of domains of MEs, cubic and hexagonal mesophasephases, varying the proportions of the components of the formulations; where in the addition of the extract did not change rheological behavior of the formulations. All of the formulations were stable in the period analyzed and presented higher bioadhesive strength. In vitro antioxidant activity suggests that LCS and MEs presented a high capacity to maintain the antioxidant activity of OC extract. The results showed that the incorporation of OC in LCS improved the safety profile, according to cytotoxicity assays of systems may be a promising platform to OC extract for topical application for the potential treatment of skin disorders. Keywords:Liquid crystals/evaluation/physical-chemical stability. Microemulsions/evaluation. Surfactant-based system. Organic cocoa extract. Skin bioadhesion. INTRODUCTIONSkin is routinely exposed to stressful environmental factors such as pollutants and UV radiation. These factors produce a large number of aggressive oxidants that damage all of the biological skin cell membranes (Silva et al., 2010;Binic et al., 2013;Datta et al., 2011;Dupont, Gomez, Bilodeau, 2013). Accordingly, the use of skin care products and cosmetics has been utilized to mitigate the cutaneous photoaging process (Visscher, Pan, Kitzmiller, 2013) and these products are commonly composed of plant extracts (Binic et al., 2013).A great number of plants and plant extracts are studied for their antioxidative action arising from their phenolic substructures. Phenolic compounds are composed of an aromatic ring that is linked to a hydroxyl group, which donates electrons and hydrogen atoms. As a result, these compounds are exceptional antioxidants (Silva et al., 2010;Binic et al., 2013;Reuter, Merfort, Schempp, 2010).Cocoa, the dried and fermented seeds derived from Theobroma cacao, has been consumed since 1100 B.C. by ancient civilizations such as the Mayans and Aztecs (Hurst et al., 2002). Cocoa contains high amounts of the flavonoids (−)-epicatechin (EC) and (+)-catechin, and procyanidins B2 and B1. Additionally, other polyphenols such as quercetin, isoquercitrin (quercetin 3-O-glucoside), quercetin 3-O-arabinose, hyperoside (quercetin 3-O-galactoside), naringenin, luteolin, and apigenin have also been found in cocoa in minor quantities (Sánchez-Rabaneda et al., 2003). While the natural amount B. Fonseca-Santos, E. E. Funagoshi, J. R. S. Olivei...

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“…액정상 에멀젼을 만드는 방법으로는 아 미노산 수용액에 친유성 계면활성제를 가하여 만드는 방법 [2], 레시틴을 이용한 유화 방법 [3], 다이팔미토일 하이드록시프롤린, 다이에탄올아민세틸포스페이트 및 제미니형 계면활성제를 이용한 액정 제조법이 보고되 었다 [4]. 또한 피부에 유분과 수분을 공급해 주는 방법 으로 액정 에멀젼을 화장품에 응용한 연구 [5] 및 각질 세포간 지질로 구성된 액정상 에멀젼 제조와 피부 보 습력과 사용감을 증진시키기 위한 연구들도 수행되었 다 [6][7][8][9][10][11]. 최근에는 피부 전달체로서의 화장품 제형에 대한 관심이 증대되면서, 저자들은 에토좀 [12], 세포 침투 펩타이드 부착 리포좀 [13], 고분자 코팅 리포좀 [14], 리포좀 인 하이드로겔 시스템 [15], 고체지질나노 입자 [16], O/W 나노에멀젼 [17] 등의 피부 전달 시스템 에 대한 연구들을 수행해 왔다.…”

Section: 서 론unclassified

Preparation of Liquid Crystal Emulsion for Transdermal Delivery of Glycyrrhizic Acid and Physical Characteristics and In Vitro Skin Permeation Studies

Jung¹,

Yoo²,

Park

2015

Journal of the Society of Cosmetic Scientists of Korea

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In this study, we prepared liquid crystal emulsion composed of amphiphilic substance C 14-22 alcohol, C 12-20 alkyl glucoside, behenyl alcohol and studied liquid crystal emulsion of properties and in vitro skin permeation. The results of formulation experiments, the clear liquid crystalline structure was observed in the ratio of C 14-22 alcohol 0.8%, C 12-20 alkyl glucoside 3.2%, behenyl alcohol 4% in the formulation. The results of physical property measurements, the viscosity of liquid crystal emulsion and O/W emulsion applied as a control group was respectively 1871.26 ∼ 1. . Hourly permeability results, it is showed that skin penetration effect of the liquid crystal emulsion increases after 8 h. These results suggest that liquid crystal emulsions are effective for skin moisturizing effect and function as potential efficacy ingredient delivery system for the transdermal delivery.Keywords: liquid crystal, rheological properties, moisturizing effect, glycyrrhizic acid, skin permeation studies, cosmetics Table 2의 liquid crystal 함량에 명시한 것과 같이 C 12-20 알킬글루코사이드는 0.2 ∼ 1.0%, C 14-22 알코올 0.8 ∼ 4.0% 그리고 베헤닐알코올은 1.0 ∼ 6.0%로 하였다. Figure 2는 제조한 샘플을 광학 현미경 400배율로 관 찰한 사진이다. C 12-20 알킬글루코사이드 0.6%, C 14-22 알코올 2.4%, 베헤닐알코올 4% 이상의 배합비에서 액 정구조의 광학 이방성 특징에 의한 maltese cross 무늬 가 비교적 선명하게 관찰되었고, C 12-20 알킬글루코사 Ingredients Contents (%)

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Study on the Formation and Properties of Liquid Crystal Emulsion in Cosmetic

Cited by 24 publications

References 9 publications

Fennel oil and by-products seed characterization and their potential applications

Fennel oil and by-products seed characterization and their potential applications

Organic cocoa extract -loaded surfactant-based systems intended to skin bioadhesion

Preparation of Liquid Crystal Emulsion for Transdermal Delivery of Glycyrrhizic Acid and Physical Characteristics and In Vitro Skin Permeation Studies

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