Study on the substitution effects of zinc benzoate terpyridine complexes on photoluminescence, antiproliferative potential and DNA binding properties

Synthesis, Characterization, Photoluminescence, Molecular Docking and Bioactivity of Zinc (II) Compounds Based on Different Substituents

“…Ligands L 1 –L 3 were prepared according to reported procedures [ 23 , 33 ]. All the complexes were synthesized by reaction of the ligands with ZnBr 2 or ZnI 2 in stoichiometric amounts, respectively.…”

“…Therefore, the interaction between complexes and proteins plays a key role in the distribution and transport of small molecules into the biological system, which affects the concentration and overall efficacy of drug molecules [ 31 ]. In our previous studies, it has been found that zinc complexes have strong antitumor activity [ 22 , 23 , 32 , 33 , 34 ]. It is noteworthy that the antitumor properties of these complexes can be regulated by the substituents at their 4′-position.…”

Solvent-driven structural topologies in phenanthroline-based co-crystals of Zn(ii) involving fascinating infinite chair-like {[(bzH)4Cl2]2−}nassemblies and unconventional layered infinite {bz-H2O-Cl}nanion-water clusters: antiproliferative evaluation and theoretical studies

“…The fourteen and ten membered supramolecular ring motifs formed in the infinite Cl-H 2 O cluster are represented using Etter's graph-set notation, 44 viz. R 6 6 (14) and R 3 3 (10), respectively. As shown in Fig.…”

“…13 Coordination complexes involving benzoic acid/benzoate ligands also possess remarkable biological applications. 14 Zinc, the second most abundant trace element in the human body, 15 plays crucial roles in cell survival by protecting tissues against damage. 16 Deficiency of zinc can depress the immune system as it plays a significant role in the immune system via cell proliferation and RNA/DNA synthesis.…”

Terpyridine functionalized cyclodextrin nanoparticles: metal coordination for tuning anticancer activity

“…29–33 In the last years, the anticancer activity of tpy and its coordination compounds has also been reported. 34–39…”