Study the effect of curcumin on hepatic DNA damage in an experimental model of hepatic fibrosis

Abstract

. AbstractBackground/aim: Curcumin, a member of the ginger family of species, has long been used to

Toxicity of Sunset Yellow FCF and Tartrazine Dyes on Dna and Cell Cycle of Liver and Kidneys of the Chick Embryo: The Alleviative Effects of Curcumin

“…The present study revealed the alleviative role of Cur against SY and Tz genotoxicity, as it reduced DNA fragmentation in hepatocytes of chick embryo. Abd-Alfattah and Abdelraouf [43] also reported a reduction in apoptotic DNA fragmentation in hepatocytes of rats treated with CCL 4 +Cur comparing with DNA extracted from hepatic tissue of rats treated with CCL 4 alone. In addition, Ghosh et al [44] revealed that Cur decreased all the streptozotocin-induced diabetic pathophysiology to male rats that induced hepatocellular apoptotic DNA fragmentation.…”