SU‐E‐J‐12: Initial Clinical Experiences in Using 4D‐CBCT as Image Guidance for Lung SBRT

Peng, Cheng; Chapman, Katherine L.; Lü, Bo; Werner‐Wasik, Maria; Yan, Yu

doi:10.1118/1.4734845

Cited by 2 publications

(2 citation statements)

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“…Symmetry automatically sorts images into ten phases based on automatic detection of diaphragm position. 31 ) do not necessarily result in higher dose compared with other protocols, which are 3D protocols. Table V also indicated that for the XVI imaging protocols, the measured doses were in good agreement with the nominal doses provided by the Vendor.…”

Section: Discussionmentioning

confidence: 93%

Comparative dose evaluations between XVI and OBI cone beam CT systems using Gafchromic XRQA2 film and nanoDot optical stimulated luminescence dosimeters

et al. 2013

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Dose response curves of Gafchromic XRQA2 film and nanoDot OSLDs indicated that the dose responses of these two dosimeters were different even at the same photon energy when different filters were used. Uncertainty levels of both dosimetry systems were below 6% at doses above 1 cGy. Both dosimetry systems gave almost similar estimation of doses (within uncertainties) in many cases, with exceptions of some cases when the discrepancy was around 20%-30%. New versions of the CBCT systems (investigated in this study) resulted in lower imaging doses compared with doses reported on earlier versions in previous studies.

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Section: Discussionmentioning

confidence: 93%

Comparative dose evaluations between XVI and OBI cone beam CT systems using Gafchromic XRQA2 film and nanoDot optical stimulated luminescence dosimeters

et al. 2013

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“…[301][302][303][304][305] Despite the aforementioned challenges, researchers have done a tremendous amount of work to address these issues, and 4D-CBCT has been shown to be of important clinical utility. Multiple studies have reported superior target visualization and increased confidence in ITV localization with 4D-CBCT technology, thereby recommending it as a more accurate image-guidance technique for moving targets as compared to 3D-CBCT, [306][307][308][309][310][311] even improving the interobserver variability. 312 Four dimensional CBCT was shown to result in dosimetric advantages via the ability to reduce margins and thus irradiate less normal tissue, 313 as well as facilitating accurate verification of target position for both inter-and intra-fractional motion for lung SBRT with VMAT delivery.…”

Section: B Investigated Solutionsmentioning

confidence: 99%

A modern review of the uncertainties in volumetric imaging of respiratory‐induced target motion in lung radiotherapy

Vergalasova

Cai

2020

Medical Physics

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Radiotherapy has become a critical component for the treatment of all stages and types of lung cancer, often times being the primary gateway to a cure. However, given that radiation can cause harmful side effects depending on how much surrounding healthy tissue is exposed, treatment of the lung can be particularly challenging due to the presence of moving targets. Careful implementation of every step in the radiotherapy process is absolutely integral for attaining optimal clinical outcomes. With the advent and now widespread use of stereotactic body radiation therapy (SBRT), where extremely large doses are delivered, accurate, and precise dose targeting is especially vital to achieve an optimal risk to benefit ratio. This has largely become possible due to the rapid development of image-guided technology. Although imaging is critical to the success of radiotherapy, it can often be plagued with uncertainties due to respiratory-induced target motion. There has and continues to be an immense research effort aimed at acknowledging and addressing these uncertainties to further our abilities to more precisely target radiation treatment. Thus, the goal of this article is to provide a detailed review of the prevailing uncertainties that remain to be investigated across the different imaging modalities, as well as to highlight the more modern solutions to imaging motion and their role in addressing the current challenges.

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SU‐E‐J‐12: Initial Clinical Experiences in Using 4D‐CBCT as Image Guidance for Lung SBRT

Abstract: 4D-CBCT is a superior image guidance technique for lung SBRT treatments for its ability to visualize moving target. It provides physicians more confidence in tumor targeting and ability to repeatedly evaluate ITV quality during the treatment course.

Cited by 2 publications

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Comparative dose evaluations between XVI and OBI cone beam CT systems using Gafchromic XRQA2 film and nanoDot optical stimulated luminescence dosimeters

Comparative dose evaluations between XVI and OBI cone beam CT systems using Gafchromic XRQA2 film and nanoDot optical stimulated luminescence dosimeters

A modern review of the uncertainties in volumetric imaging of respiratory‐induced target motion in lung radiotherapy

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